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HIV and tuberculosis in Durban, South Africa: adherence to two medication regimens.

机译：南非德班的艾滋病毒和结核病：遵守两种药物治疗方案。

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Given that antiretroviral (ARV) medication adherence has been shown to be high in resource-limited countries, the question remains as to whether adherence will remain at that level as medications become more widely available. Comparing adherence to tuberculosis (TB) medications, which have been readily available, and ARV medications may help to indicate the likely future adherence to ARVs as access to these medications becomes more widespread. This study examined sense of coherence, social support, symptom status, quality of life, and adherence to medications in two samples of individuals being treated either for TB or human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) at clinics in Durban, South Africa. Findings revealed the distinctive socio-economic backgrounds of the two cohorts. Although there were significant differences with regard to the psychosocial variables, there were no significant differences by the two samples in adherence to medications as well as adherence to appointments. Given the self-selected nature of the participants in this study, namely those able to attend clinic, as well as those likely to be adherent to ARVs, there is every reason for caution in the interpretations of these findings. As access to ARV medications becomes more widely available in South Africa, the question remains as to whether such high adherence will be maintained given the constraints of access to food and other basic necessities.
机译：鉴于在资源有限的国家中抗逆转录病毒（ARV）药物依从性很高，因此随着药物的广泛使用，依从性是否会保持在该水平仍是一个问题。比较已经很容易获得的对结核病（TB）药物的依从性，以及抗逆转录病毒药物的使用可能有助于表明随着对这些药物的获取越来越广泛，未来对抗逆转录病毒药物的依从性。这项研究在南德班的诊所检查了两个接受结核病或人类免疫缺陷病毒/后天免疫缺陷综合症（HIV / AIDS）治疗的个体样本中的一致性感，社会支持，症状状态，生活质量以及对药物的依从性非洲。调查结果揭示了这两个队列的独特社会经济背景。尽管在心理社会变量方面存在显着差异，但两个样本在遵守药物和遵守约会方面没有显着差异。考虑到本研究参与者（即能够去诊所的人以及可能坚持抗逆转录病毒疗法的人）的自我选择性质，在解释这些发现时，有充分的理由谨慎。随着南非越来越多地获得抗逆转录病毒药物的使用，鉴于获得食物和其他基本必需品的限制，是否会保持如此高的依从性仍是一个问题。

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