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Reducing vertical HIV transmission in Kinshasa, Democratic Republic of Congo: trends in HIV prevalence and service delivery.

机译:减少刚果民主共和国金沙萨的艾滋病毒垂直传播:艾滋病毒流行率和服务提供趋势。

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摘要

Scale-up of vertical HIV transmission prevention has been too slow in sub-Saharan Africa. We describe approaches, challenges, and results obtained in Kinshasa. Staff members of 21 clinics managed by public servants or non-governmental organizations were trained in improved basic antenatal care (ANC) including nevirapine (NVP)-based HIV transmission prevention. Program initiation was supported on-site logistically and technically. Aggregate implementation data were collected and used for program monitoring. Contextual information was obtained through a survey. Among 45,262 women seeking ANC from June 2003 through July 2005, 90% accepted testing; 792 (1.9%) had HIV of whom 599 (76%) returned for their result. Among 414 HIV+ women who delivered in participating maternities, NVP coverage was 79%; 92% of newborns received NVP. Differences were noted by clinic management in program implementation and HIV prevalence (1.2 to 3.0%). Initiating vertical HIV transmission prevention embedded in improved antenatal services in a fragile, fragmented, severely resource-deprived health care system was possible and improved over time. Scope and quality of service coverage should further increase; strategies to decrease loss to follow-up of HIV+ women should be identified to improve program effectiveness. The observed differences in HIV prevalence highlight the importance of selecting representative sentinel surveillance centers.
机译:在撒哈拉以南非洲,垂直的艾滋病毒传播预防工作的推广速度太慢。我们描述了金沙萨的方法,挑战和获得的结果。由公务员或非政府组织管理的21家诊所的工作人员接受了包括基于奈韦拉平(NVP)的HIV传播预防在内的改善的基本产前保健(ANC)的培训。程序启动在后勤和技术上得到了现场支持。收集了总体实施数据并将其用于程序监视。上下文信息是通过调查获得的。 2003年6月至2005年7月,有45262名寻求ANC的女性中,有90%接受了检测; 792人(1.9%)感染了艾滋病毒,其中599人(76%)感染了艾滋病毒。在参与分娩的414名HIV +妇女中,NVP覆盖率为79%; 92%的新生儿接受了NVP。诊所管理人员在计划实施和HIV感染率方面发现差异(1.2%至3.0%)。在脆弱,零散,资源严重匮乏的卫生保健系统中,有可能在改善的产前服务中嵌入垂直的HIV传播预防措施,随着时间的推移,这种预防措施将得到改善。服务范围和质量应进一步提高;应当确定减少对HIV +妇女进行随访的损失的策略,以提高计划的有效性。观察到的艾滋病毒流行率差异突出显示了选择代表性的前哨监测中心的重要性。

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