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首页> 外文期刊>AIDS care. >Perceived stigma among patients receiving antiretroviral therapy: a prospective study in KwaZulu-Natal, South Africa.
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Perceived stigma among patients receiving antiretroviral therapy: a prospective study in KwaZulu-Natal, South Africa.

机译：接受抗逆转录病毒治疗的患者中的可耻污名：南非夸祖鲁-纳塔尔省的一项前瞻性研究。

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The aim of this study is to examine whether internalized AIDS stigma among HIV patients one year after antiretroviral therapy (ART) initiation is associated with sociodemographic characteristics, health status, social support, quality of life (QoL), and ARV adherence. This is a prospective study of all treatment-naive patients (N=735) recruited from all three public hospitals in Uthukela health district in KwaZulu-Natal and followed up at 6 and 12 months being on ART. Results indicated that despite a decrease in stigma seen in this study (may be due to ART) the level of stigma and discrimination remains high, and stigma reduction interventions are urgently needed in this population. CD4 cell counts significantly increased and HIV symptoms reduced significantly but depression symptoms remained high and even increased after 12 months on treatment. In multivariate analysis lower CD4 cell counts (odds ratio 0.5, 0.3-0.9), severe depression (5.6, 2.5-12.5) and low QoL (0.6, 0.5-0.8) were associated with internalized AIDS stigma. These findings may suggest that HIV care should include counseling and support that includes stigma concerns, depression, and QoL prior to and during the first year following diagnosis.
机译：这项研究的目的是检查抗逆转录病毒疗法（ART）启动一年后HIV患者中的内部AIDS污名是否与社会人口统计学特征，健康状况，社会支持，生活质量（QoL）和ARV依从性相关。这是对从夸祖鲁-纳塔尔省乌苏基拉健康区的所有三家公立医院招募的所有未接受治疗的患者（N = 735）的一项前瞻性研究，并在接受ART的6和12个月进行了随访。结果表明，尽管在这项研究中发现耻辱感有所降低（可能是由于抗逆转录病毒治疗所致），但耻辱感和歧视水平仍然很高，因此该人群迫切需要减少耻​​辱感干预措施。治疗12个月后，CD4细胞计数显着增加，HIV症状显着减少，但抑郁症状仍然很高，甚至有所增加。在多变量分析中，较低的CD4细胞计数（几率0.5、0.3-0.9），严重抑郁（5.6、2.5-12.5）和低QoL（0.6、0.5-0.8）与内在的AIDS柱头相关。这些发现可能表明，在诊断前和诊断后的第一年中，艾滋病毒的护理应包括咨询和支持，包括污名，忧郁症和生活质量。

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