Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

Wood Michelle E.; Stockwell Rebecca E.; Johnson Graham R.; Ramsay Kay A.; Sherrard Laura J.; Kidd Timothy J.; Cheney Joyce; Ballard Emma L.; ORourke Peter; Jabbour Nassib; Wainwright Claire E.; Knibbs Luke D.; Sly Peter D.; Morawska Lidia; Bell Scott C.

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Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

机译：囊性纤维化病原体在咳嗽产生的液滴内的延长时期存活

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The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured.

机译：空气中的途径是囊性纤维化（CF）群体中的细菌菌株的人对型群体的潜在途径。在这种横断面研究中，我们研究了在咳嗽期间产生的常见非假单胞菌铜绿假单胞菌病原体的物理性质和存活。我们得出结论，在咳嗽期间，革兰氏阴性细菌和金黄色葡萄球菌是气溶病的，可以在液滴中行进4米，在液滴核内保持可行，可达45分钟。这些结果表明，我们测量的CF病原体是合理的空气传播的。

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来源
《Thorax: The Journal of the British Thoracic Society》 |2019年第1期|共4页
作者
Wood Michelle E.; Stockwell Rebecca E.; Johnson Graham R.; Ramsay Kay A.; Sherrard Laura J.; Kidd Timothy J.; Cheney Joyce; Ballard Emma L.; ORourke Peter; Jabbour Nassib; Wainwright Claire E.; Knibbs Luke D.; Sly Peter D.; Morawska Lidia; Bell Scott C.;
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作者单位

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

Queensland Univ Technol Int Lab Air Qual &

Hlth Brisbane Qld Australia;

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

Lady Cilento Childrens Hosp Dept Resp &

Sleep Med South Brisbane Qld Australia;

QIMR Berghofer Med Res Inst Stat Unit Herston Qld Australia;

QIMR Berghofer Med Res Inst Stat Unit Herston Qld Australia;

Queensland Univ Technol Int Lab Air Qual &

Hlth Brisbane Qld Australia;

Univ Queensland Fac Med Brisbane Qld Australia;

Univ Queensland Sch Publ Adm Herston Qld Australia;

Univ Queensland Fac Med Brisbane Qld Australia;

Queensland Univ Technol Int Lab Air Qual &

Hlth Brisbane Qld Australia;

QIMR Berghofer Med Res Inst Lung Bacteria Grp Herston Qld Australia;

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原文格式 PDF
正文语种 eng
中图分类呼吸系及胸部疾病;
关键词
cystic fibrosis; infection control;

机译：囊性纤维化;感染控制;

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专利

1. Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei [J] . Wood Michelle E., Stockwell Rebecca E., Johnson Graham R., Thorax: The Journal of the British Thoracic Society . 2019,第1期

机译：囊性纤维化病原体在咳嗽产生的液滴内的延长时期存活
2. "Cystic fibrotics could survive cholera, choleraics could survive cystic fibrosis"; hypothesis that explores new horizons in treatment of cystic fibrosis [J] . Medical hypotheses . 2015,第6期

机译：“囊性纤维化可以抵抗霍乱，霍乱患者可以抵抗囊性纤维化”;假说探索治疗囊性纤维化的新视野
3. FACE MASKS AND COUGH ETIQUETTE REDUCE COUGH-GENERATED BIOAEROSOLS CONTAINING PSEUDOMONAS AERUGINOSA IN PATIENTS WITH CYSTIC FIBROSIS [J] . Wood M. E., Stockwell R., Johnson G., Pediatric Pulmonology . 2016,第Suppla51期

机译：囊性纤维化患者的面膜和凝集性肠溶减少形成凝集性铜绿假单胞菌的生物气溶胶
4. STRUCTURE OF ENDOTOXIN FROM OPPORTUNIST CYSTIC FIBROSIS PATHOGENS [C] . Silipo A., Di Lorenzo F, Elefante C International Carbohydrate Symposium . 2013

机译：机会主义囊性纤维化病原体内毒素的结构
5. Emerging Pathogens in Cystic Fibrosis Patients at Virginia Commonwealth University Medical Center (VCUMC). [D] . Hill, Emily Marie. 2016

机译：弗吉尼亚联邦大学医学中心（VCUMC）的囊性纤维化患者中的新兴病原体。
6. Cough-generated aerosols of Pseudomonas aeruginosa and other Gram-negative bacteria from patients with cystic fibrosis [O] . C E Wainwright, M W France, P O’Rourke, -1

机译：囊性纤维化患者咳嗽产生的铜绿假单胞菌气溶胶和其他革兰氏阴性细菌
7. Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei [O] . Michelle E Wood, Rebecca E Stockwell, Graham R Johnson, 2018

机译：囊性纤维化病原体在咳嗽产生的液滴内的延长时期存活

Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

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