Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention

Bai Xiao-Fang; Zhang Ya-Ping; Zhou Juan; Wu Yue; Li Rui-Feng; Sun Li-Zhe; Ma Qiang-Qiang; Lou Bo-Wen; Zhai Bo-Wen; Liu Meng-Ping; Cheng Le-Le; Tong Xiao-Ning; Yuan Zu-Yi

首页> 外文期刊>Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis >Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention

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Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention

机译：CYP2C19代谢物的组合和优雅风险得分更好地预测急性冠状动脉综合征中经皮冠状动脉介入的长期主要不良心脏事件

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Introduction: Both Global Registry of Acute Coronary Events (GRACE) risk score and CYP2C19 metabolizer status can independently predict major adverse cardiac events (MACEs) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). We investigated whether their combination could better predict MACE occurrence in patients with ACS undergoing PCI.

机译：简介：急性冠状动脉事件（Grace）风险评分和CYP2C19代谢物状态的全球注册机构可以独立地预测经皮冠状动脉干预（PCI）的急性冠状动脉综合征（ACS）患者中的主要不良心脏事件（拟合）。我们调查了他们的组合是否可以更好地预测ACS接受PCI的ACS患者的姿态发生。

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来源
《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis》 |2018年第2018期|共6页
作者
Bai Xiao-Fang; Zhang Ya-Ping; Zhou Juan; Wu Yue; Li Rui-Feng; Sun Li-Zhe; Ma Qiang-Qiang; Lou Bo-Wen; Zhai Bo-Wen; Liu Meng-Ping; Cheng Le-Le; Tong Xiao-Ning; Yuan Zu-Yi;
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作者单位

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xian 4 Hosp Jie Fang Rd Xian 710004 Shaanxi Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

Xi An Jiao Tong Univ Affiliated Hosp 1 Med Lab Xian Shaanxi Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Cardiovasc Med Dept Ultrasound Imaging;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Acute coronary syndrome; CYP2C19 metabolizer; GRACE score; Risk factor; Prognosis;

机译：急性冠状动脉综合征;CYP2C19代谢物;恩典分数;危险因素;预后;

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1. Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention [J] . Bai Xiao-Fang, Zhang Ya-Ping, Zhou Juan, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2018,第期

机译：CYP2C19代谢物的组合和优雅风险得分更好地预测急性冠状动脉综合征中经皮冠状动脉介入的长期主要不良心脏事件
2. A new score for risk stratification of patients with acute coronary syndromes undergoing percutaneous coronary intervention: The ACUITY-PCI (Acute Catheterization and Urgent Intervention Triage Strategy-Percutaneous Coronary Intervention) risk score [J] . JACC. Cardiovascular interventions . 2012,第11期

机译：经皮冠状动脉介入治疗的急性冠脉综合征患者危险分层的新评分：ACUITY-PCI（急性导管插入和紧急干预分类策略-经皮冠状动脉介入治疗）风险评分
3. Gender is Not a Predictor of Mortality or Major Adverse Cardiovascular Events in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes [J] . Josiah Angeline, Farshid Ahmad Heart, lung & circulation . 2019,第5期

机译：性别不是在经皮冠状动脉综合征的经皮冠状动脉介入的患者中的死亡率或主要不良心血管事件的预测因素
4. Risk Prediction Models for Major Adverse Cardiac Event (MACE) Following Percutaneous Coronary Intervention (PCI): A review [C] . Norhafizah A Manan, Basir Abidin ISM International Statistical Conference . 2015

机译：经皮冠状动脉干预后主要不良心脏事件（PCI）的风险预测模型（PCI）：综述
5. The Association between Unfractionated Heparin and Bivalirudin Used during Percutaneous Coronary Intervention for Stable Angina and Acute Coronary Syndromes and the In-Hospital and Mortality Outcomes Observed across All Body Mass Index Groups [D] . Chen, Christine. 2021

机译：在所有体重指数群体中观察到稳定冠状动脉干预期间使用经皮冠状动脉介入和急性冠状动脉综合征的冠状动脉介入和医院和死亡率结果之间的联合肝素和Bivalirudin之间的关联
6. Adjustment of the GRACE score by HemoglobinA1c enables a more accurate prediction of long-term major adverse cardiac events in acute coronary syndrome without diabetes undergoing percutaneous coronary intervention [O] . Xiao-Jun Liu, Zhao-Fei Wan, Na Zhao, 2015

机译：通过血红蛋白A1c调节GRACE评分可以更准确地预测急性冠脉综合征的长期主要不良心脏事件而无需糖尿病患者进行经皮冠状动脉介入治疗
7. Adjustment of the GRACE score by HemoglobinA1c enables a more accurate prediction of long-term major adverse cardiac events in acute coronary syndrome without diabetes undergoing percutaneous coronary intervention [O] . Xiao-Jun Liu, Zhao-Fei Wan, Na Zhao, 2015

机译：通过血红蛋白A1c调节GRACE评分，可以更准确地预测急性冠脉综合征的长期主要不良心脏事件，而无需糖尿病患者进行经皮冠状动脉介入治疗

Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention

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