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Cases of HIV type 1 acute infection at STI-related clinics in Osaka.

机译:大阪的性传播感染相关诊所的HIV 1型急性感染病例。

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Since 1992 we have investigated HIV antibodies in persons with a venereal disease who worked for a sex business or engaged in sexual behavior with a high risk of HIV infection at five clinics of venereology, urology, and gynecology in Osaka Prefecture. Starting at the end of 2000, we performed a nucleic acid-amplification test (NAT) on antibody-negative samples with the aim of detecting cases in the window period covering the early phase of infection. Three cases that were thought to be in this phase were found in 2006. All were confirmed to be positive in an NAT, although they were negative in initial screening for HIV performed using the IC method. Gene analysis of the env-C2V3 region of HIV-1 showed that the three samples had different origins.
机译:自1992年以来,我们在大阪府的5个性病,泌尿科和妇科诊所调查了性病患者的HIV抗体,这些患者从事性工作或从事性行为且感染HIV的风险很高。从2000年底开始,我们对抗体阴性样品进行了核酸扩增测试(NAT),目的是在涵盖感染早期的窗口期内检测病例。 2006年发现了三例被认为处于这一阶段的病例。尽管在使用IC方法进行的HIV初步筛查中均为阴性,但在NAT中均被确认为阳性。对HIV-1的env-C2V3区域进行的基因分析表明,这三个样品的来源不同。

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