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首页> 外文期刊>AIDS Research and Human Retroviruses >Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa.
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Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa.

机译:来自南非开普敦的非合胞体诱导型HIV 1型D亚型菌株的完整基因组测序。

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摘要

The fast growing HIV-1 epidemic in South Africa is mainly caused by HIV-1 group M subtype C, spreading via heterosexual transmission. In South Africa HIV-1 subtype B and D viruses were responsible for the initial epidemic during the 1980s, primarily in the homosexual population. This study describes the full-length PCR amplification and sequencing of an HIV-1 subtype D strain recovered from plasma from a sample taken during 1990. This is only the second full-length non-syncytium-inducing (NSI) subtype D strain described. Although restricted, the subtype D strain is still being detected in the South African population.
机译:南非快速增长的HIV-1流行主要是由HIV-1 M型C亚型引起的,通过异性传播传播。在南非,HIV-1 B和D型亚型病毒是1980年代初期流行的主要原因,主要是在同性恋人群中。这项研究描述了从1990年采集的样本中从血浆中回收的HIV-1 D型亚型的全长PCR扩增和测序。这只是描述的第二种全长非合胞体诱导(NSI)D型亚型。尽管受到限制,但仍在南非人群中检测到D型亚型。

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