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首页> 外文期刊>AIDS Research and Human Retroviruses >Interarm blood pressure differences in the women's interagency HIV study.
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Interarm blood pressure differences in the women's interagency HIV study.

机译：妇女机构间艾滋病毒研究中的臂间血压差异。

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Hypertension has been reported in 8-32% of HIV-infected individuals. Large interarm blood pressure differences (IABPD) may cause misclassification of blood pressure (BP) status. The objectives of this study were to determine the magnitude and factors associated with IABPD in HIV-infected women and uninfected controls. Using automated devices, two BP recordings were measured and averaged from each arm in Brooklyn enrollees of the Women's Interagency HIV Study. Absolute IABPD was calculated for each patient. Among 335 subjects, 238 were HIV infected and 97 were uninfected. Mean systolic and diastolic IABPD were 6 +/- 5 mm Hg and 4 +/- 3 mm Hg, respectively. Twenty-six percent of subjects had systolic IABPD >10 mm Hg and 6% had systolic IABPD >20 mm Hg. Fifteen percent of subjects had diastolic IABPD >10 mm Hg. Interarm BP differences were not associated with HIV serostatus, CD4(+) cell count, and use of highly active antiretroviral therapy. Systolic IABPD >20 mm Hg was associated with obesity (ORadj 5.37, 95% CI 1.47, 19.65), and LDL cholesterol above 160 (ORadj 9.12, 95% CI 2.53, 32.88). Right arm BP measurement resulted in 10% of subjects with high/uncontrolled BP. Bilateral arm BP measurement increased the yield to 15% (p < 0.001). In conclusion, systolic and diastolic IABPD are common and appear to be of clinically important magnitude. Systolic IABPD are related to cardiovascular risk factors but not to HIV-related factors. Bilateral BP determination is important to detect and manage hypertension as well as for accurate cardiovascular risk assessment.
机译：据报道，有8-32％的HIV感染者患有高血压。较大的手臂间血压差（IABPD）可能导致血压状态（BP）的分类错误。这项研究的目的是确定感染HIV的妇女和未感染对照中与IABPD相关的程度和因素。在妇女机构间艾滋病研究的布鲁克林入组者中，使用自动化设备测量了两个BP记录，并平均每个臂的BP记录。计算每位患者的绝对IABPD。在335名受试者中，有238名感染了HIV，97名未感染。平均收缩压和舒张压IABPD分别为6 +/- 5 mm Hg和4 +/- 3 mm Hg。 26％的受试者的收缩期IABPD> 10 mm Hg，6％的收缩期IABPD> 20 mm Hg。 15％的受试者舒张压IABPD> 10 mm Hg。臂间BP差异与HIV血清状况，CD4（+）细胞计数以及高活性抗逆转录病毒疗法的使用无关。收缩期IABPD> 20 mm Hg与肥胖症相关（ORadj 5.37，95％CI 1.47，19.65）和LDL胆固醇高于160（ORadj 9.12，95％CI 2.53，32.88）。右臂血压测量导致10％的受试者血压高/不受控制。双边手臂血压测量可将收率提高到15％（p <0.001）。总之，收缩期和舒张期IABPD很常见，并且在临床上具有重要意义。收缩期IABPD与心血管危险因素有关，但与HIV相关因素无关。双边血压测定对于检测和控制高血压以及准确的心血管风险评估非常重要。

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