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首页> 外文期刊>AIDS care. >Methamphetamine abuse as a barrier to HIV medication adherence among gay and bisexual men.
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Methamphetamine abuse as a barrier to HIV medication adherence among gay and bisexual men.

机译：甲基苯丙胺滥用是男同性恋和双性恋男性中艾滋病毒药物依从性的障碍。

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Medication adherence among persons with HIV infection is important not only because of the effect of non-adherence on an individual's health but also because non-adherence can lead to medication-resistant viral strains. However, adherence to HIV medications is difficult due to complex dosing regimens and side effects. This paper is a qualitative analysis of HIV medication adherence among gay and bisexual methamphetamine-abusing men enrolled in an outpatient drug treatment research project. As part of an open-ended, semi-structured interview, 23 HIV-infected men discussed the effects of their methamphetamine use on their medication adherence. Substance-use barriers to adherence were coded into two main themes: (1) planned non-adherence and (2) unplanned non-adherence. Planned non-adherence was a strategy for coping with demanding HIV medication schedules, or was linked to sexual behaviours while using methamphetamine or to fears of interaction effects from mixing methamphetamine with HIV medications. Participants did not define their medication regimen adjustments as non-adherence but as a way to achieve a sense of control over their lives. Unplanned non-adherence was linked to methamphetamine-related disruptions in food and sleep schedules. Findings are helpful in designing culturally specific HIV medication adherence interventions for this population.
机译：HIV感染者之间的药物依从性很重要，这不仅是因为不依从会对个人健康造成影响，而且还因为不依从会导致耐药性病毒株。但是，由于复杂的给药方案和副作用，很难坚持使用HIV药物。本文是对参加门诊药物治疗研究项目的同性恋和双性恋甲基苯丙胺滥用男性中艾滋病毒药物依从性的定性分析。作为不限成员名额，半结构化访谈的一部分，23名受HIV感染的男人讨论了甲基苯丙胺的使用对其依从性的影响。物质使用的遵守障碍被编码为两个主要主题：（1）计划内的不遵守和（2）计划外的不遵守。计划中的不依从性是应对苛刻的HIV药物治疗方案的一种策略，或者与使用甲基苯丙胺时的性行为有关，或者担心将甲基苯丙胺与HIV药物混合会产生相互作用。参加者并未将他们的用药方案调整定义为不依从，而是将其视为对生活进行控制的一种方式。计划外的不坚持与食物和睡眠时间表中与甲基苯丙胺相关的中断有关。这些发现有助于设计针对该人群的文化特定的HIV药物依从性干预措施。

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