HIV type 1 genetic diversity in Moyale, Mandera, and Turkana based on env-C2-V3 sequences.

Khamadi SA; Lihana RW; Mwaniki DL; Kinyua J; Lagat N; Carter JY; Ichimura H; Oishi I; Okoth FA; Ochieng W

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HIV type 1 genetic diversity in Moyale, Mandera, and Turkana based on env-C2-V3 sequences.

机译：基于env-C2-V3序列的Moyale，Mandera和Turkana中的HIV 1型遗传多样性。

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The genetic diversity of HIV-1 subtypes circulating in three districts of northern Kenya, i.e., Turkana, Mandera, and Moyale, was studied. DNA sequences encoding a portion of the env-C2-V3 region of the virus were amplified by PCR and sequenced directly. One hundred and fifty-nine samples were successfully sequenced in the env-C2-V3 region and analyzed. From the analysis, 57% were subtype A1, 27% were subtype C, 9% were subtype D, and the remaining 7% were unclassified. This study showed that HIV-1 subtype A1 was the dominant subtype in circulation in this region, though there was a significant percentage of HIV-1 subtype C in circulation there.

机译：研究了在肯尼亚北部三个地区（即图尔卡纳，曼德拉和莫亚莱）传播的HIV-1亚型的遗传多样性。通过PCR扩增编码病毒的env-C2-V3区域的一部分的DNA序列并直接测序。在env-C2-V3区域成功测序了159个样品并进行了分析。根据分析，A1型为57％，C型为27％，D型为9％，其余7％为未分类。这项研究表明，尽管该地区的HIV-1亚型C占相当大的比例，但该地区的HIV-1亚型A1是该循环中的主要亚型。

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《AIDS Research and Human Retroviruses》 |2008年第12期|共4页
作者
Khamadi SA; Lihana RW; Mwaniki DL; Kinyua J; Lagat N; Carter JY; Ichimura H; Oishi I; Okoth FA; Ochieng W;
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正文语种 eng
中图分类传染病;
关键词
Child; Cluster Analysis; DNA; Viral; Epidemiology; Molecular; Female; Genetic Variation; 儿童; 聚类分析; DNA; 病毒; 流行病学; 分子; 基因型; HIV感染; 肯尼亚; 分子序列数据;

机译：Child;Cluster Analysis;DNA;Viral;Epidemiology;Molecular;Female;Genetic Variation;儿童;聚类分析;DNA;病毒;流行病学;分子;基因型;HIV感染;肯尼亚;分子序列数据;

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1. HIV type 1 genetic diversity in Moyale, Mandera, and Turkana based on env-C2-V3 sequences. [J] . Khamadi SA, Lihana RW, Mwaniki DL, AIDS Research and Human Retroviruses . 2008,第12期

机译：基于env-C2-V3序列的Moyale，Mandera和Turkana中的HIV 1型遗传多样性。
2. Impact of Human Immunodeficiency Virus Type 1 (HIV-1) Genetic Diversity on Performance of Four Commercial Viral Load Assays: LCx HIV RNA Quantitative, AMPLICOR HIV-1 MONITOR v1.5, VERSANT HIV-1 RNA 3.0, and NucliSens HIV-1 QT [J] . Priscilla Swanson, Carmen de Mendoza, Yagnya Joshi, Journal of Clinical Microbiology . 2005,第8期

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3. Potential impact of viral load and genetic makeup of HIV type 1 on mother-to-child transmission: characterization of env-C2V3C3 and nef sequences. [J] . Padua E, Parreira R, Tendeiro AIDS Research and Human Retroviruses . 2009,第11期

机译：病毒载量和1型HIV的遗传组成对母婴传播的潜在影响：env-C2V3C3和nef序列的表征。
4. Can Simple GAs Solve Beehive Hidato Logic Puzzles? The Influence of Diversity Preservation and Genetic Operators [C] . Matheus M. Pereira da Silva, Camila S. De Magalhães IEEE Congress on Evolutionary Computation . 2018

机译：简单的GA可以解决蜂巢Hidato Logic难题吗？多样性保护和遗传算子的影响
5. Genetic Diversity of RT-SHIV Viremia and Viral Reservoirs in a Non-human Primate Model of Human HIV-1 Highly Active Antiretroviral Therapy. [D] . Kauffman, Robert Clark. 2014

机译：RT-SHIV病毒血症和病毒库的遗传多样性在人类HIV-1高效抗逆转录病毒疗法的非人类灵长类动物模型中。
6. Impact of Human Immunodeficiency Virus Type 1 (HIV-1) Genetic Diversity on Performance of Four Commercial Viral Load Assays: LCx HIV RNA Quantitative AMPLICOR HIV-1 MONITOR v1.5 VERSANT HIV-1 RNA 3.0 and NucliSens HIV-1 QT [O] . Priscilla Swanson, Carmen de Mendoza, Yagnya Joshi, 2005

机译：人类免疫缺陷病毒1型（HIV-1）遗传多样性对四种商业病毒载量分析性能的影响：LCx HIV RNA定量AMPLICOR HIV-1 MONITOR v1.5VERSANT HIV-1 RNA 3.0和NucliSens HIV-1 QT

HIV type 1 genetic diversity in Moyale, Mandera, and Turkana based on env-C2-V3 sequences.

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