首页> 外文期刊>Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research >Monitoring of pesticide applicators for potential dermal exposure to malathion and biomarkers in urine.
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Monitoring of pesticide applicators for potential dermal exposure to malathion and biomarkers in urine.

机译:对农药施用器的监测,尿液中的潜在皮肤暴露于尿液和生物标志物。

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摘要

Malathion was applied to roses in three Finnish greenhouses by hand held lance sprayers. The potential dermal exposure of applicators to this insecticide was measured. Total urine production of each applicator was also collected up to 24 h post application. In the urine samples the specific metabolite of malathion, malathion monocarboxylic acid (MMA), and the creatinine content were determined. The potential dermal exposure results show that during the application of malathion, the applicators' lower limbs accounted, on average, for 48%, while the upper limbs accounted for 19% of the potential dermal exposure. Moreover, hands and chest and back and head regions accounted for 30 and 3%, respectively. Based on the urine measurements, it was observed that the excretion of MMA was very rapid reaching a maximum at about 6-7 h after the completion of the application. In the urine samples collected, MMA was found to be present in relatively small amounts.
机译:手工持有的喷枪喷雾器将马拉氏植入三个芬兰温室中的玫瑰。 测量涂抹器对该杀虫剂的潜在皮肤暴露。 每个涂药器的尿液总产量也被收集到申请后24小时。 在尿液中,测定马拉硫磷脂酸酯的特异性代谢物,并测定肌酸酐含量。 潜在的真皮暴露结果表明,在施用马拉硫磷期间,施用者的下肢平均占48%,而上肢占潜在皮肤暴露的19%。 此外,手和胸部和背部和头部区域分别占30%和3%。 基于尿液测量,观察到在施用完成后,MMA的排泄在约6-7小时内极快地达到最大值。 在收集的尿液样本中,发现MMA以相对较少的量存在。

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