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Immunoglobulin abnormalities in 1677 solid organ transplant recipients. Implications for posttransplantation follow-up

机译:1677个固体器官移植受者的免疫球蛋白异常。 对后翻盖的影响随访

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摘要

Background: Posttransplant lymphoproliferative disorder (PTLD) is a severe complication of solid organ transplantation (SOT). However, there is no consensus on PTLD screening methods. Gammopathies (GP), which occur in 10-25% of SOT recipients, have been linked to subsequent development of PTLD. Therefore, GP detection methods, such as serum protein electrophoresis (SPE), serum protein immunofixation (SIFE), urine protein immunofixation (UIFE) and the quantitative measurement of serum free light chains (SFLC) are candidate methods for PTLD screening.
机译:背景:后翻盖淋巴抑制剂(PTLD)是固体器官移植(SOT)的严重并发症。 但是,对PTLD筛选方法没有共识。 在10-25%的SOT受体中发生的血曲调(GP)已与PTLD的后续发展有关。 因此,GP检测方法,例如血清蛋白电泳(SPE),血清蛋白免疫混膜(SIFE),尿蛋白免疫链(UIFE)和血清自由链(SFLC)的定量测量是PTLD筛选的候选方法。

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  • 来源
    《Transplant immunology》 |2019年第2019期|共10页
  • 作者单位

    Charles Univ Prague Fac Med 3 Ruska 2411-87 Prague Czech Republic;

    Charles Univ Prague Fac Med 3 Ruska 2411-87 Prague Czech Republic;

    Charles Univ Prague Fac Med 3 Ruska 2411-87 Prague Czech Republic;

    Karolinska Inst Dept Neurobiol Care Sci &

    Soc Div Clin Geriatr Blickagangen 16 Neo Sweden;

    Inst Clin &

    Expt Med Dept Lab Methods Videnska 1958-9 Prague 14021 Czech Republic;

    Inst Clin &

    Expt Med Dept Organ Harvesting &

    Transplantat Databases Videnska 1958-9 Prague;

    Charles Univ Prague Fac Med 3 Ruska 2411-87 Prague Czech Republic;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 器官移植术;
  • 关键词

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