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The effects of hyperthermic intraperitoneal chemoperfusion on colonic anastomosis: an experimental study in a rat model

机译:高温腹膜内校长对结肠吻合术的影响:大鼠模型的实验研究

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Introduction: Cytoreductive surgery (CRS) with subsequent hyperthermic intraperitoneal chemotherapy (HIPEC) is a promising modality to treat and prevent peritoneal metastases. However, this treatment is associated with signficant morbidity and mortality. Whether or not CRS with HIPEC interferes with anastomotic healing has also been debated. This study was designed to investigate the effects of mitomycin C, cisplatin, oxaliplatin, and doxorubicin used in HIPEC treatment on colonic anastomosis healing in a rat model.
机译:简介:随后的热热腹膜内化疗(HIPEC)的细胞功能性术(CRS)是治疗和预防腹膜转移的有希望的模态。 然而,这种治疗与意义发病率和死亡率有关。 与HIPEC的CRS是否干扰吻合术治疗也得到争论。 本研究旨在探讨丝霉素C,顺铂,奥沙利铂和多柔比星用于大鼠模型中结肠吻合术治疗的影响。

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