T‐cell receptor and B‐cell receptor repertoire profiling in adaptive immunity

Minervina Anastasia; Pogorelyy Mikhail; Mamedov Ilgar

首页> 外文期刊>Transplant international : >T‐cell receptor and B‐cell receptor repertoire profiling in adaptive immunity

【24h】

T‐cell receptor and B‐cell receptor repertoire profiling in adaptive immunity

机译：T细胞受体和B细胞受体在适应性免疫中的剖面

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Summary B‐cell receptors and T‐cell receptors are the key molecules responsible for specific antigen recognition in adaptive immunity. The huge diversity of immune receptor repertoires constrained their comprehensive studies in the past. More recently, however, high‐throughput sequencing based techniques have revolutionized the field of immune receptor repertoire profiling enabling new insights into the development and function of the adaptive immune system. In this review we describe current methods for immune receptor profiling and software tools used for repertoire reconstruction from raw sequencing data. We also provide examples of how immune repertoire profiling can be used to study adaptive immunity in disease and in the course of organ and bone marrow transplantation.

机译：发明内容B细胞受体和T细胞受体是负责适应性免疫中特异性抗原识别的关键分子。巨大的免疫受体曲目多样性在过去约束了他们的综合研究。然而，最近，基于高通量测序的技术已经彻底改变了免疫受体曲目分析领域，从而实现了新的洞察自适应免疫系统的开发和功能。在本文中，我们描述了从原始测序数据中用于reptoIre重建的免疫接收器分析和软件工具的现有方法。我们还提供了如何使用免疫重新遗传的例子来研究疾病和器官和骨髓移植过程中的适应性免疫。

著录项

来源
《Transplant international :》 |2019年第11期|共13页
作者
Minervina Anastasia; Pogorelyy Mikhail; Mamedov Ilgar;
展开▼
作者单位

Department of Genomics of Adaptive ImmunityM M Shemyakin and Yu A Ovchinnikov Institute of;

Department of Genomics of Adaptive ImmunityM M Shemyakin and Yu A Ovchinnikov Institute of;

Department of Genomics of Adaptive ImmunityM M Shemyakin and Yu A Ovchinnikov Institute of;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类器官移植术;
关键词
adaptive immunity; repertoire sequencing;

机译：自适应免疫;曲目测序;

相似文献

外文文献
中文文献
专利

1. T‐cell receptor and B‐cell receptor repertoire profiling in adaptive immunity [J] . Minervina Anastasia, Pogorelyy Mikhail, Mamedov Ilgar Transplant international : . 2019,第11期

机译：T细胞受体和B细胞受体在适应性免疫中的剖面
2. The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells) [J] . Hughes Francis M. Jr., Turner David P., Purves J. Todd International Urology and Nephrology . 2015,第12期

机译：膀胱先天免疫系统的潜在功能：在大鼠膀胱和大鼠尿路上皮细胞系（MYP3细胞）中模式识别受体的表达
3. The role of the class A scavenger receptors, SR-A and MARCO, in the immune system. Part 1. The structure of receptors, their ligand binding repertoires and ability to initiate intracellular signaling [J] . Szczepan Józefowski Post?py Higieny i Medycyny Do?wiadczalnej . 2012,第1期

机译：A类清除剂受体SR-A和MARCO在免疫系统中的作用。第1部分。受体的结构，它们的配体结合库和启动细胞内信号传导的能力
4. Classification of the States of Human Adaptive Immune Systems by Analyzing Immunoglobulin and T Cell Receptors Using ImmunExplorer [C] . Susanne Schaller, Johannes Weinberger, Raul Jimenez-Heredia, International conference on computer aided systems theory . 2015

机译：通过使用ImmunExplorer分析免疫球蛋白和T细胞受体，对人类适应性免疫系统的状态进行分类
5. Triggering receptor expressed on myeloid cells 2 (TREM-2) molecule: Biochemistry, counter-receptors, and functions in innate and adaptive immunity [D] . Goode, Diana J. 2012

机译：在髓样细胞2（TREM-2）分子上表达的触发受体：生化，抗受体及其在先天和适应性免疫中的功能
6. Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling [O] . Johannes Trück, Anne Eugster, Pierre Barennes, 2021

机译：适应性免疫受体曲目分析标准化和解释的生物学控制
7. Development of adaptive immune cells and receptor repertoires from infancy to adulthood [O] . Johannes Trück, Mirjam van der Burg 2020

机译：从婴儿期到成年期的自适应免疫细胞和受体曲目的发展

T‐cell receptor and B‐cell receptor repertoire profiling in adaptive immunity

摘要

著录项

相似文献

相关主题

期刊订阅