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首页> 外文期刊>Tropical Animal Health and Production >Efficacy of VERYL (R) in the treatment of cattle naturally infected with gastro-intestinal nematodes in Kenya
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Efficacy of VERYL (R) in the treatment of cattle naturally infected with gastro-intestinal nematodes in Kenya

机译：高效（R）在肯尼亚胃肠线虫治疗牛治疗中的疗效

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Co-infections caused by trypanosomes and gastro-intestinal nematodes (GINs) compromise cattle productivity and their control requires a holistic approach. The effectiveness of trypanocides and anthelmintics is compromised by increasing resistance. Use of combined chemotherapeutic products for synergy, mainly practiced in human medicine, is gaining importance in livestock. A trial to evaluate efficacy of VERYL (R), containing diminazene diaceturate (3.5 mg/kg body weight) and levamisole chloride (5 mg/kg body weight) for the control of GINs in cattle, was conducted at KALRO-VSRI Muguga, Kenya, between June and August 2016. Thirty-eight cattle aged between 6 and 12 months, naturally infected with GINs, were randomly allocated into two groups; a treatment group received VERYL (R) intra-muscularly at 10 mL/100 kg bwt and a control group which received Veriben (R) (Diminazene aceturate) at 3.5 mg/kg bwt. Faecal egg counts (FECs), coproculture, packed cell volume (PCV) and local tolerance at the injection site were measured during the study. FECs were comparable between the treatment and control groups at day 0. However, treatment of cattle with VERYL significantly (p < 0.001) reduced FECs by day 7 and sustained to day 21 post-treatment. Coproculture results for the treatment and control groups revealed presence ofHaemonchus,Cooperia,Ostertagia,TrichostrongylusandOesophagostomumspecies. Cattle treated with VERYL (R) had a significant (p < 0.05) reduction in larval recoveries compared to the control group. VERYL (R) had minimal adverse effects which cleared after a short while and is thus recommended for controlling GINs in cattle.
机译：由锥虫和胃肠线虫（杜松子酒）损害牛生产率及其对照引起的共感染需要整体方法。通过耐药性损害胰蛋白酶和触角蛋白的有效性。使用合并的化学治疗产品进行协同作用，主要在人体医学中实行，在牲畜中取得重要意义。在Kalro-Vsrimuguga，肯尼亚进行了对牛中谷蛋白（3.5mg / kg体重）和Levamisole氯化物（5mg / kg体重）和左旋氨酸氯化物（5mg / kg体重）和左旋氨酸氯化物（5mg / kg体重）进行试验。 ，2016年6月至8月期间，在6至12个月之间的三十八岁，天然感染杜松子蛋白，随机分配为两组;治疗组在10mL / 100kg BWT的10mL / 100kg BWT和对照组接受肌肉内肌肉，并在3.5mg / kg bwt下接受veriben（二嗪醋酸酯）的对照组。在研究期间测量粪便卵数（FECS），共培养，包装细胞体积（PCV）和注射部位的局部耐受性。在第0天的治疗和对照组之间是可比的。然而，在第7天和第21天持续到治疗后第21天，牛的治疗和对照组之间的治疗和对照组之间的比较相当。治疗和对照组的共产培养结果显示出存在的存在，Coceria，Ostertagia，TrichostrongylusandoOphagostompecies。与对照组相比，用GiSl（R）治疗的牛在幼虫回收率降低了显着的（p <0.05）。在短时间内，Suerl具有最小的不良反应，因此建议在牛中控制胶水饼。

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