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Assessment of meat quality defect genes in indigenous pigs of Bareilly region

机译：巴伊利地区土着猪肉质量缺陷基因评估

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摘要

This investigation was undertaken to assess the population of indigenous (Bareilly local) pigs for meat quality genes (RYR1, PRKAG3, HFABP, MYF-5, and MC4R). The results showed that indigenous pigs were monomorphic at RYR1locus (100% NN genotype), HFABP locus (100% HH genotype), and MYF-5 locus (100% DD genotype). Homozygote RR and heterozygote QR genotypes were observed at PRKAG3 (c.599 G>A) SNP locus with 89 and 11% frequency. The frequency of wild (R) and mutant (Q) allele at the said locus was 95 and 5%. The MC4R SNP had three genotypes; homozygote AA with 5% frequency, heterozygote AG with 53% frequency, and homozygote GG with 42% frequency. Corresponding frequency of A and G allele was 32 and 68%, respectively. Monomorphic status at RYR1locus for NN genotype, HFABP locus for HH genotype, and MYF-5 locus for DD genotype indicated that favorable genes for quality pork production have been fixed in the population. The higher frequency of RR genotype (89%) at PRKAG3 and GG genotype (42%) at MC4R locus further explained the existence of favorable genotypes in indigenous pigs.
机译：进行了这项调查，以评估肉质基因的土着（Bareilly局部）猪（Ryr1，Prkag3，HFABP，MyF-5和MC4R）的人口。结果表明，土着猪在Ryr1斑点（100％NN基因型），HFABP基因座（100％HH基因型）和MyF-5基因座（100％DD基因型）中是单体的。在Prkag3（C.599g> a）SNP基因座上观察到Homozygote RR和杂合子QR基因型，其具有89和11％频率。所述基因座的野生（R）和突变体（Q）等位基因的频率为95和5％。 MC4R SNP有三个基因型; Homozygote AA具有5％的频率，杂合子效应具有53％的频率，并且具有42％频率的Homozygote Gg。相应的A和G等位基因的频率分别为32和68％。对于HH基因型的HFABP基因型Ryr1Locus的单数状态，以及DD基因型的MyF-5基因座，表明优质猪肉产量的有利基因已在人口中得到固定。 MC4R基因座在Prkag3和GG基因型（42％）的RR基因型（89％）的频率进一步解释了本土猪中有利基因型的存在。

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