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Sensitivity and specificity of the FAMACHA((c)) system in tropical hair sheep

机译：热带毛发绵羊的Famacha（（c））系统的敏感性和特异性

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The aim of this research was to evaluate the sensitivity and specificity of the FAMACHA((c)) (F-(c)) system in Morada Nova ewes. The conjunctivae of 562 ewes were evaluated using the F-(c) system. Packed cell volume (PCV) served as the gold standard for clinical F-(c) evaluation. To calculate the sensitivity and specificity of the F-(c) system, different criteria were adopted: animals classified as (I) F-(c) 4 and 5 or (II) 3, 4, and 5 were considered to be anemic and animals classified as (I) F-(c) 1, 2, and 3, or (II) 1 and 2 were considered to be non-anemic. Three standard values of PCV, namely, 19%, 18%, or 15%, were used to confirm anemia. The percentage of correct treatments was always high when the F-(c) values 4 and 5 were used as criteria for positive tests. For all the PCV cut-off values, more animals were classified as false positives when evaluated using F-(c) 3, 4, and 5 as criteria for a positive test and more true negative animals when evaluated using only F-(c) 4 and 5 as criteria for a positive test. For both sets of criteria for the positive tests, few animals were classified as false negatives and true positives. Eliminating the classification of F-(c) 3 as anemic decreased the sensitivity and increased the specificity for all the PCV cut-off values for the ewes. The F-(c) system can be used as a reliable alternative to reduce selection pressure for anthelmintics in relation to routine non-selective blanket treatment for worm control in the Morada Nova ewes.
机译：该研究的目的是评估Morada Nova EWES的Famacha（（c））（f-（c））系统的敏感性和特异性。使用F-（C）系统评估562母羊的结膜。包装细胞体积（PCV）用作临床F-（c）评估的金标准。为了计算F-（C）系统的敏感性和特异性，采用不同的标准：分类为（i）（c）4和5或（ii）3,4和5的动物被认为是贫血和将动物分类为（i）F-（c）1,2和3，或（ii）1和2被认为是非贫血的。 PCV的三个标准值，即19％，18％或15％用于确认贫血。当F-（c）值4和5用作正检测标准时，正确处理的百分比总是高。对于所有PCV截止值，当使用F-（C）3,4和5作为阳性测试和更真实的阴性动物的标准评估使用时，更多的动物被归类为误报，因为仅使用F-（c）如图4和5所示的正面测试标准。对于两组标准的阳性测试，很少有动物被归类为虚假否定和真实的积极态度。消除F1（c）3的分类，因为贫血降低了敏感性，并增加了母羊的所有PCV截止值的特异性。 F-（C）系统可用作可靠的替代方案，以减少与莫拉达新母羊在莫拉达控制中的蠕虫控制的常规非选择性毯子治疗方面的选择压力。

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