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首页> 外文期刊>Tropical Animal Health and Production >Effects of L-glutamine on rectal temperature and some markers of oxidative stress in Red Sokoto goats during the hot-dry season
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Effects of L-glutamine on rectal temperature and some markers of oxidative stress in Red Sokoto goats during the hot-dry season

机译：热干燥季节红路山羊红外山羊直肠温度及氧化应激的影响的影响

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摘要

The experiment investigated the ameliorative effects of l-glutamine administration on rectal temperature (RT), erythrocyte osmotic fragility (EOF), serum antioxidant enzyme activities and malondialdehyde (MDA) concentration in Red Sokoto goats during the hot-dry season. Twenty eight healthy Red Sokoto goats, comprising 14 experimental (administered 0.2 g/kg of l-glutamine dissolved in 10 mL of distilled water, once daily for 21 days) and 14 control (administered equivalent of distilled water) goats served as subjects. Rectal temperature (measured at 6:00, 13:00 and 18:00 h) and blood samples (taken at 8:00 h) were obtained from all subjects weekly, before, during and after l-glutamine administration. Data obtained were compared using one-way repeated-measures ANOVA, followed by Tukey's post-hoc test. The dry-bulb temperature, relative humidity and temperature-humidity index for the study period ranged between 24.0 and 37.5 A degrees C, 26.0 and 84.0% and 73.0 and 86.3, respectively. l-glutamine administration decreased (P 0.05) RT, EOF and MDA and increased superoxide dismutase (SOD) activity in experimental group, compared to controls during weeks 1, 2 and 3. Glutathione peroxidase (GPx) and catalase activities were higher (P 0.05) in the experimental group than in the controls only during week 1 of l-glutamine administration. In conclusion, l-glutamine administration mitigated increases in RT, EOF and serum MDA concentration and enhanced serum SOD, GPx and catalase activities and may be beneficial in heat-stressed goats during the hot-dry season.
机译：该实验研究了在热干燥季节期间，在热干燥季节期间研究了L-谷氨酰胺给药对直肠温度（RT），红细胞渗透脆性（EOF），血清抗氧化酶活性和丙二醛（MDA）浓度的改善作用。二十八个健康的红色Sokoto山羊，包含14个实验（将0.2g / kg溶解在10ml蒸馏水中的L-谷氨酰胺，每天21天一次）和14个对照（施用当量的蒸馏水）山羊作为受试者。直肠温度（6:00，13:00和18:00 h）和血液样本（8:00 h）每周，在L-谷氨酰胺给药之前，期间和之后从所有受试者那里获得。使用单向反复测量Anova进行比较所获得的数据，然后进行Tukey的Hoc测试。研究时期的干泡温度，相对湿度和温度湿度指数分别在24.0和37.5℃，26.0和84.0％和73.0和86.3之间。 L-谷氨酰胺给药降低（P <0.05）RT，EOF和MDA，实验组中的超氧化物歧化酶（SOD）活性增加，与第1周内的对照相比，2和3.谷胱甘肽过氧化物酶（GPX）和过氧化氢酶活性更高（ P＆ 0.05）在实验组中，仅在L-谷氨酰胺给药的第1周期间的对照。总之，L-谷氨酰胺给药缓解在RT，EOF和血清MDA浓度和增强的血清SOD，GPX和过氧化氢酶活性增加，并且在热干燥季节期间可能是有益的。

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