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首页> 外文期刊>Tropical Animal Health and Production >Administration of a single dose of a PGF2 alpha analogue (dinoprost) before sexual tests did not improve ram's sexual behaviour
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Administration of a single dose of a PGF2 alpha analogue (dinoprost) before sexual tests did not improve ram's sexual behaviour

机译：在性试验之前施用单一剂量的PGF2α类似物（DinoProost）没有改善RAM的性行为

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The aim of this study was to determine if a single administration of dinoprost tromethamine before each test enhances sexual behaviour in inexperienced rams, and if the possible effect is maintained after the rams gain sexual experience. The study was conducted in northeaster Mexico during autumn (breeding season). The study was performed with 26 Saint Croix rams (16.1 +/- 1.1 months old). Rams were allocated to two treatments, which were subjected to 15 tests with 2 restrained non-oestrous ewes. While rams from one group (group DIN) received a single dose of dinoprost (10 mg im, Lutalyse, Zoetis) immediately before the test, the other rams remained untreated (group CON). Sexual behaviours were recorded during 5 min. The data were analysed with a mixed model that included the treatment, number of test and their interaction as main effects, and the individual as a random effect. DIN rams displayed less ano-genital sniffings (6.6 +/- 0.8 vs 9.7 +/- 0.8,P = 0.007), matings (0.11 +/- 0.05 vs 0.29 +/- 0.05,P = 0.03), and had a lower mating/total mounts ratio (0.05 +/- 0.03 vs 0.16 +/- 0.03,P = 0.006) than CON rams. There were no other treatment effects, but there were significant effects of time and interactions between treatment and time in all the behaviours. Overall, administration of a single dose of dinoprost before testing did not have positive effects in the development of rams' sexual behaviour, and even, might have negative effects. However, it should be considered that in this study only one prostaglandin analogue, one dose of this analogue, administered immediately before the tests was used, so more studies involving other analogues, doses, and/or regimes of administration should be done.
机译：本研究的目的是确定每次测试之前单次施用DinoProost Trometomine是否在不经验的公羊中增强了性行为，如果在公羊获得性经验后保持可能的效果。该研究在墨西哥秋季（繁殖季节）在墨西哥东部进行进行。该研究患有26个Saint Croix Rams（16.1 +/- 1.1个月）进行。将RAM分配给两种治疗，其与2个受约束的非令人愉快的非令人垂母羊进行了15个试验。虽然从一组（组DIN）的RAMS在测试前接受单剂量DinoProost（10mg，Lutalyse，Zoetis），但其他RAM仍未治疗（组CON）。在5分钟内记录了性行为。通过混合模型分析数据，其中包括治疗，测试数及其相互作用作为主要效果，以及个体作为随机效应。 DIN RAM显示较少的Ano-Genital Sniffings（6.6 +/- 0.8 Vs 9.7 +/- 0.8，P = 0.007），聚合物（0.11 +/- 0.05 Vs 0.29 +/- 0.05，P = 0.03），并具有较低的交配/总安装比率（0.05 +/- 0.03 Vs 0.16 +/- 0.03，p = 0.006），而不是CON RAM。没有其他治疗效果，但在所有行为中的治疗与时间之间存在显着影响和相互作用。总体而言，在测试前施用单剂量Dinopostost在RAM的性行为发展中没有积极影响，甚至可能产生负面影响。然而，应该认为在本研究中只有一个前列腺素类似物，一种剂量的这种类似物，立即在使用之前施用，因此应采取更多的研究涉及其他类似物，剂量和/或给药的制度。

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