...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Veterinary Parasitology >In vitro assessment of the acaricidal activity of carvacrol, thymol, eugenol and their acetylated derivatives on Rhipicephalus microplus (Acari: Ixodidae)
【24h】

In vitro assessment of the acaricidal activity of carvacrol, thymol, eugenol and their acetylated derivatives on Rhipicephalus microplus (Acari: Ixodidae)

机译：对爬血液中的爬行动物，胸腺酚，丁香酚及其乙酰化衍生物的杀螨活性的体外评估（Acari：Ixodidae）

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This study reports the comparative evaluation of the activity of carvacrol, thymol, eugenol and their respective acetylated derivatives (carvacrol acetate, thymol acetate and eugenol acetate) on Rhipicephalus microplus, to verify the possible influence of the acetate group. The acetylated derivatives were prepared from reactions of the phenolic compounds with acetic anhydride/pyridine. The formation of the products was confirmed by analysis of hydrogen and carbon-13 nuclear magnetic resonance (H-1 and C-13 NMR) spectra. The larval packet test was used to evaluate the acaricidal activity, with concentrations of 0.312, 0.625, 1.25, 2.5, 5.0, 7.5, 10.0 and 15.0 mg/mL. Thymol and carvacrol resulted in 100% mortality starting at the concentration of 2.5 mg/mL, while the same was observed for carvacrol acetate starting at the concentration of 5.0 mg/mL. For the other treatments, 100% mortality was only achieved in the groups treated with the highest concentration (15.0 mg/mL). The LC50 and LC90 values (mg/mL) of carvacrol acetate (2.49, 4.21), thymol acetate (2.97, 8.52) and eugenol acetate (4.25, 13.10) were higher than those for the corresponding precursor molecules carvacrol (0.83, 2.02), thymol (1.26, 2.21) and eugenol (2.77, 5.35). The acetylation process did not enhance the activity of these substances on unengorged larvae of R. microplus, since the precursor substances (carvacrol, thymol and eugenol) had greater efficacy.
机译：本研究报告了对Rapicephalus微孔的钙伐，胸腺，丁醇，丁烯醇及其各自的乙酰化衍生物（糖醋酸盐，苯乙酸盐醋酸盐醋酸盐）的比较评价，以验证乙酸酯基团的可能影响。乙酰化衍生物由酚类化合物与乙酸酐/吡啶的反应制备。通过分析氢气和碳-13核磁共振（H-1和C-13 NMR）光谱来确认产品的形成。使用幼虫分组试验来评估杀螨剂活性，浓度为0.312,0.625,1.25,2.5,5.0,7.5,10.0和15.0mg / ml。胸腺醇和胰酸钙导致浓度为2.5mg / ml的浓度100％的死亡率，而仅针对浓度为5.0mg / ml的血糖乙酸盐。对于其他治疗，仅在最高浓度（15.0mg / ml）处理的基团中才能实现100％的死亡率。 LC50和LC90值（Mg / ml）碳酸醋酸盐（2.49,4.21），胸腺酚醋酸盐（2.97,8.52）和醋酸丁醇酯（4.25,13.10）高于相应的前体分子爬行物（0.83,2.02），胸腺（1.26,2.21）和丁香酚（2.77,5.35）。乙酰化方法没有增强这些物质对R. microplus的未预算幼虫的活性，因为前体物质（Carvacrol，Thymol和丁烯醇）有更大的功效。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号