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Necrotizing eosinophilic dermatitis in three dogs

机译:在三只狗的坏死性嗜酸性皮肤病

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In this paper, necrotizing eosinophilic dermatitis with an acute onset and a rapidly progressive clinical course is reported in three dogs. Early skin lesions were characterized by intensely pruritic, erythem atolls and firm intact papules and plaques. The lesions enlarged and evolved quickly into coalescing nodular target shaped lesions with central exudation, ulceration and necrosis. The lesion distribution pattern was mainly the neck and the dorsolateral trunk. Oral involvement was observed in one dog. The histopathology was characterized by eosinophilic dermatitis and panniculitis targeting dermal and subcutaneous blood vessels with secondary involvement of hair follicles. While causation remained unproven in these cases, a hypersensitivity reaction to medications or other foreign antigens was suspected.
机译:本文在三只狗中报道了具有急性发作和迅速进行的临床课程的坏死性嗜酸性皮炎。 早期皮肤病变的特征是强烈的瘙痒,红斑环礁和坚定的丘疹和斑块。 损伤扩大并迅速进化到聚结节的结节靶形病变,中央渗出,溃疡和坏死。 病变分布图案主要是颈部和背侧躯干。 在一只狗中观察口腔参与。 组织病理学的特征在于嗜酸性皮炎和Panniculitis靶向皮肤和皮下血管,其具有毛囊的二次累积。 虽然在这些情况下,因果发生未经证实,但怀疑对药物或其他外来抗原的过敏反应。

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