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首页> 外文期刊>Water Quality, Exposure and Health >Human Health Risk Assessment of Chromium in Drinking Water: A Case Study of Sukinda Chromite Mine, Odisha, India
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Human Health Risk Assessment of Chromium in Drinking Water: A Case Study of Sukinda Chromite Mine, Odisha, India

机译：饮用水中铬的人体健康风险评估 - 以印度Odisha，Otisha Chromite Line的案例研究

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摘要

The present study aims to evaluate human health risk of Cr(VI) and Cr(III) via oral and dermal exposure of drinking water in groundwater samples of nearby Sukinda chromite mine. The risk assessment of each location was carried out using mathematical models as per IRIS guidelines and the input parameters were taken according to the Indian context. The concentrations of TCr and Cr(VI) were found in the range of 48.7-250.2 and 21.4-115.2 μg/l, respectively. In the maximum locations, TCr and Cr(VI) concentrations were found 2.3-6 times and 2.1-11.5 times higher, respectively, than the permissible limit as per standard statutory bodies. The total cumulative average cancer risk and non-cancer risk (Hazard Quotient) was found 2.04E-03 and 1.37 in male and 1.73E-03 and 1.16 in the female population, respectively, which indicated 'very high' cancer risk and 'medium' non-cancer risk as per USEPA guideline. Male population was found 1.2 times higher cancer and non-cancer risk than females, because of the higher water ingestion rate in male. The obtained health risk via dermal route was found 6 times lesser than the oral ingestion due to very less dermal exposure time (0.58 h/days). As a consequence, 'high' cancer risk also recorded in one of the locations where TCr concentration was within permissible limit which is because of the higher proportion of bioavailable Cr(VI). Sensitivity analysis of input parameters towards cancer and non-cancer risk revealed that Cr(VI) and Cr(III) concentrations were the main predominant parameters followed by exposure duration, body weight, average time, and dermal slope factor.
机译：本研究旨在通过附近Sukinda Chromite Lime的地下水样本中的口服和皮肤暴露来评估Cr（VI）和Cr（III）的人类健康风险。根据虹膜指南，使用数学模型进行每个位置的风险评估，并且根据印度语境采取输入参数。 TCR和Cr（VI）的浓度分别在48.7-250.2和21.4-115.2μg/ L的范围内。在最大位置，PCR和Cr（VI）浓度分别比标准法定机构的允许极限相比，分别比允许的极限更高2.3-6倍，2.1-11.5倍。累积平均癌症风险和非癌症风险（危害商）分别在雌性人群中发现2.04E-03和1.37，分别在雌性人群中，表明了“非常高”的癌症风险和“中等” '非癌症风险根据使用者指南。由于男性的含水摄入率较高，癌症癌症和非癌症风险的癌症和非癌症风险的群体群体具有1.2倍。由于非常较低的暴露时间（0.58小时），通过皮肤途径获得的健康风险比口服摄入较小6倍。因此，“高”癌症风险还记录在其中TCR浓度在允许极限内的一个位置，这是因为生物可利用的CR（VI）比例较高。对癌症和非癌症风险的输入参数的敏感性分析表明，Cr（VI）和Cr（III）浓度是曝光持续时间，体重，平均时间和皮肤斜率因子的主要主要参数。

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