> Ischemic heart disease is the leading cause of mortality worldwide. The purpose of this study was to evaluate the cardioprotecti'/> Cardioprotective Effects of Pomegranate ( <fc xmlns='http://www.wiley.com/namespaces/wiley'> <fi>Punica granatum</fi> </fc> <fi xmlns='http://www.wiley.com/namespaces/wiley'>Punica granatum</fi>Punica granatum ) Juice in Patients with Ischemic Heart Disease
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首页> 外文期刊>Phytotherapy research: PTR >Cardioprotective Effects of Pomegranate ( Punica granatum Punica granatumPunica granatum ) Juice in Patients with Ischemic Heart Disease
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Cardioprotective Effects of Pomegranate ( Punica granatum Punica granatumPunica granatum ) Juice in Patients with Ischemic Heart Disease

机译：石榴的心脏保护作用（ punica granatum punica granatum 淡紫色格拉纳特杂烩”

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> Ischemic heart disease is the leading cause of mortality worldwide. The purpose of this study was to evaluate the cardioprotective effects of pomegranate juice in patients with ischemic heart disease. One hundred patients, diagnosed with unstable angina or myocardial infarction, were randomly assigned to the test and the control groups ( n ?=?50, each). During 5?days of hospitalization, in addition to the conventional medical therapies, the test groups received 220?mL pomegranate juice, daily. During the hospitalization period, the blood pressure, heart rate, as well as the intensity, occurrence, and duration of the angina were evaluated on a regular basis. At the end of the hospitalization period, the serum levels of malondialdehyde, interleukin‐6, and tumor necrosis factor alpha were measured in all patients. The levels of serum troponin and high‐sensitive C‐reactive protein levels were also assayed in patients diagnosed with myocardial infarction. Pomegranate juice caused significant reductions in the intensity, occurrence, and duration of angina pectoris in patients with unstable angina. Consistently, the test patients had significantly lower levels of serum troponin and malondialdehyde. Other studied parameters did not change significantly. The results of this study suggest protective effects of pomegranate juice against myocardial ischemia and reperfusion injury. Copyright ? 2017 John Wiley & Sons, Ltd.
机译： >缺血性心脏病是全世界死亡率的主要原因。本研究的目的是评估石榴汁在缺血性心脏病患者中的心脏保护作用。诊断出患有不稳定的心绞痛或心肌梗死的一百名患者被随机分配给测试和对照组（ N =Δ50）。在5日的住院期间，除了传统的医疗疗法之外，测试组每天接受220？ml石榴汁。在住院期间，定期评估血压，心率，强度，发生血管的强度，发生和持续时间。在住院期结束时，在所有患者中测量丙炔醛，白细胞介素-6和肿瘤坏死因子α的血清水平。在诊断患有心肌梗死的患者中也测定血清肌钙蛋白和高敏感的C反应蛋白水平的水平。石榴汁导致不稳定的心绞痛患者心绞痛，发生和持续时间的显着减少。始终如一地，测试患者血清肌钙蛋白和丙二醛的含量显着降低。其他研究参数没有显着变化。本研究的结果表明石榴汁对心肌缺血再灌注损伤的保护作用。版权？ 2017年John Wiley＆amp; SONS，LTD。

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