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Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study.

机译:减少CT辐射剂量的迭代重建技术:可行性研究。

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OBJECTIVE: The purpose of this study was to evaluate the image noise, low-contrast resolution, image quality, and spatial resolution of adaptive statistical iterative reconstruction in low-dose body CT. MATERIALS AND METHODS: Adaptive statistical iterative reconstruction was used to scan the American College of Radiology phantom at the American College of Radiology reference value and at one-half that value (12.5 mGy). Test objects in low- and high-contrast and uniformity modules were evaluated. Low-dose CT with adaptive statistical iterative reconstruction was then tested on 12 patients (seven men, five women; average age, 67.5 years) who had previously undergone routine-dose CT. Two radiologists blinded to scanning technique evaluated images of the same patients obtained with routine-dose CT and low-dose CT with and without adaptive statistical iterative reconstruction. Image noise, low-contrast resolution, image quality, and spatial resolution were graded on a scale of 1 (best) to 4 (worst). Quantitative noise measurements were made on clinical images. RESULTS: In the phantom, low- and high-contrast and uniformity assessments showed no significant difference between routine-dose imaging and low-dose CT with adaptive statistical iterative reconstruction. In patients, low-dose CT with adaptive statistical iterative reconstruction was associated with CT dose index reductions of 32-65% compared with routine imaging and had the least noise both quantitatively and qualitatively (p < 0.05). Low-dose CT with adaptive statistical iterative reconstruction and routine-dose CT had identical results for low-contrast resolution and nearly identical results for overall image quality (grade 2.1-2.2). Spatial resolution was better with routine-dose CT (p = 0.004). CONCLUSION: These preliminary results support body CT dose index reductions of 32-65% when adaptive statistical iterative reconstruction is used. Studies with larger statistical samples are needed to confirm these findings.
机译:目的:本研究的目的是评估低剂量机体CT中自适应统计迭代重建的图像噪声,低对比度分辨率,图像质量和空间分辨率。材料与方法:采用自适应统计迭代重建技术在美国放射学院参考值和该值的一半(12.5 mG​​y)处扫描美国放射学院体模。对低对比度和高对比度以及均匀性模块中的测试对象进行了评估。然后对先前接受常规剂量CT的12例患者(七名男性,五名女性;平均年龄67.5岁)进行了具有自适应统计迭代重建的低剂量CT测试。两名放射科医生对扫描技术不了解,评估了使用常规剂量CT和低剂量CT在有和没有自适应统计迭代重建的情况下对同一患者的图像。图像噪声,低对比度分辨率,图像质量和空间分辨率的等级为1(最佳)到4(最差)。在临床图像上进行定量噪声测量。结果:在幻像中,低对比度,高对比度和均匀性评估显示常规剂量成像和低剂量CT与自适应统计迭代重建之间无显着差异。在患者中,与常规成像相比,具有自适应统计迭代重建功能的低剂量CT与CT剂量指数降低32-65%有关,并且在定量和定性方面的噪音均最小(p <0.05)。具有自适应统计迭代重建功能的低剂量CT和常规剂量CT的低对比度分辨率结果相同,而总体图像质量的结果几乎相同(2.1-2.2级)。常规剂量CT的空间分辨率更好(p = 0.004)。结论:这些初步结果支持使用自适应统计迭代重建时将身体CT剂量指数降低32-65%。需要用更大的统计样本进行研究以证实这些发现。

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