• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Headache >Symptoms of Autonomic Dysfunction Among Those With Persistent Posttraumatic Headache Attributed to Mild Traumatic Brain Injury: A Comparison to Migraine and Healthy Controls
【24h】

Symptoms of Autonomic Dysfunction Among Those With Persistent Posttraumatic Headache Attributed to Mild Traumatic Brain Injury: A Comparison to Migraine and Healthy Controls

机译：持续性故障性头痛的自主功能障碍症状归因于轻度创伤性脑损伤：与偏头痛和健康对照的比较

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Most persistent posttraumatic headaches (PPTH) have a phenotype that meets diagnostic criteria for migraine or probable migraine. Although symptoms of autonomic dysfunction have been well described among those with migraine, the presence and relative severity of such symptoms among those with PPTH have yet to be reported. Objective The objective of this study was to assess and compare symptoms of autonomic dysfunction among those with PPTH attributed to mild traumatic brain injury (mTBI) vs migraine vs healthy controls using Composite Autonomic Symptom Score 31 (COMPASS‐31) questionnaire scores. Methods Individuals with PPTH (n?=?56) (87.5% of whom had a migraine/probable migraine phenotype), migraine (n?=?30), and healthy controls (n?=?36) were prospectively assessed in this cross‐sectional cohort study using the COMPASS‐31 questionnaire. Total COMPASS‐31 scores and individual domain scores (bladder, gastrointestinal, orthostatic intolerance, pupillomotor, secretomotor, vasomotor) were compared between subject groups. Results COMPASS‐31 mean total weighted score was 37.22?±?15.44 in the PPTH group, 27.15?±?14.37 in the migraine group, and 11.67?±?8.98 for healthy controls. COMPASS‐31 mean weighted total scores were significantly higher in those with PPTH vs migraine ( P ?=?.014), for PPTH vs healthy controls ( P ?=?.001), and for migraine vs healthy controls ( P ?=?.001). Those with PPTH had numerically higher scores for all COMPASS‐31 domains compared to those with migraine, and the domain scores were significantly higher for orthostatic intolerance (PPTH?=?4.80?±?2.47 vs migraine?=?3.33?±?2.31, P ?=?.027) and bladder (PPTH?=?1.14?±?1.45 vs migraine?=?0.47?±?0.73, P ?=?.020). Among individuals with PPTH, post hoc correlations indicated a positive association between number of total lifetime TBIs with total weighted COMPASS‐31 scores (rho?=?0.32, P ?=?.020), between years lived with headache and vasomotor domain subscores (rho?=?0.27; P ?=?.044), and between headache frequency with vasomotor domain subscores (rho?=?0.27; P ?=?.041). Conclusions Symptoms of autonomic dysfunction were greatest among those with PPTH compared to migraine and healthy controls. Among individuals with PPTH, number of lifetime TBIs was associated with greater symptoms of autonomic dysfunction, while greater headache burden was associated with higher vasomotor domain autonomic dysfunction subscores, potentially indicating that PPTH patients with higher disease burden have an increased risk for having autonomic dysfunction. Symptoms of autonomic dysfunction should be ascertained during the clinical management of patients with PPTH and might be a characteristic that helps differentiate PPTH from migraine.
机译：背景技术大多数持久性的前后头痛（PPTH）具有满足偏头痛或可能偏头痛的诊断标准的表型。虽然具有偏头痛的自主功能障碍的症状已经很好地描述，但尚未报告具有PPTH的这些症状的存在和相对严重程度。目的本研究的目的是评估和比较归因于轻度创伤性脑损伤（MTBI）与使用复合自主症状评分31（Compass-31）调查问卷分数的患有轻度创伤性脑损伤（MTBI）的PPTH中的自主功能障碍的症状。方法PPTH的个体（N？=？56）（其中87.5％有偏头痛/可能偏头痛表型），偏头痛（n？=？30），并在这十字架中探讨了健康的对照（n？=？36）使用Compass-31问卷调查队列研究。在受试者组之间比较了总罗盘-31分数和个体结构域分数（膀胱，胃肠道，原版不耐受，瞳孔，分泌物，血管瘤）。结果COMPACT-31平均加权总分为PPTH组中的37.22±15.44℃，27.15°COMPER组，27.15〜±14.37，11.67？±8.98用于健康控制。 Compass-31平均重量的总分比在ppth偏头痛（p？= 014）中显着较高（p？= 014），用于ppth与健康对照（p？=Δ.001），以及用于偏头痛与健康对照（p？=？ .001）。与偏头痛相比，所有COMPAR-31结构域的PPTH的分数具有数值更高的分数，并且域分数对于直疏图（PPTH？=α.4.80？±2.47 VS偏头痛？=？3.33？±2.31， p？= 027）和膀胱（ppth？=？1.14？±1.45 Vs偏头痛？=？0.47？±020）。在具有PPTH的个体中，HOC相关性相关的次数与总加权罗斯-31分数的总寿命TBIS（RHO？= 0.32，P？=Δ.020）之间存在正相关性，几年与头痛和血管传递域名（ rho？=？0.27; p？=？044），并且与血管传离域亚峰值的头痛频率（rho？= 0.27; p？= 041）。结论与偏头痛和健康对照相比，PPTH的自主功能障碍症状最大。在具有PPTH的个体中，终身TBI的数量与自主功能障碍的更大症状有关，而更高的头痛负担与较高的血管瘤域自主功能障碍群相关，可能表明PPTH患者患有更高的疾病负担的患者具有自主功能障碍的风险增加。在PPTH患者的临床管理期间，应确定自主功能功能障碍的症状，并且可能是有助于区分偏头痛的ppth的特征。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号