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首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Outcome analysis of 9-gauge MRI-guided vacuum-assisted core needle breast biopsies.
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Outcome analysis of 9-gauge MRI-guided vacuum-assisted core needle breast biopsies.

机译：9口径MRI引导的真空辅助芯针乳房活检的结果分析。

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OBJECTIVE: The purpose of this article is to correlate 9-gauge MRI-guided vacuum-assisted breast biopsy with surgical histologic findings to determine the upgrade rate and to correlate the frequency of MRI-guided vacuum-assisted breast biopsy cancer diagnosis with breast MRI indications and enhancement characteristics of targeted lesions. MATERIALS AND METHODS: A database search was performed of all MRI-guided vacuum-assisted breast biopsies performed from January 1, 2005, to September 31, 2010. The breast MRI indications, history, age, risk factors, lesion size, enhancement characteristics, and pathologic diagnoses at MRI-guided vacuum-assisted breast biopsy and at surgery were documented. Fisher exact test and analysis of variance were used for statistical analysis. RESULTS: A total of 218 lesions underwent MRI-guided vacuum-assisted breast biopsy in 197 women (mean age, 52 years; range, 28-76 years), of which 85 (39%) had surgical correlation. Of the 218 lesions, 48 (22%) were malignant, 133 (61%) were benign, and 37 (17%) were high risk according to MRI-guided vacuum-assisted breast biopsy. Ten of 85 lesions (12%) were upgraded to malignancy at surgery, with a final malignancy rate of 25%. The frequency of malignancy was significantly higher in patients presenting for diagnostic (50/177 [28%]) versus screening (4/41 [10%]; p < 0.05) evaluation, patients with ipsilateral cancer (22/49 [45%]; p < 0.001), and lesions with washout kinetics (34/103 [33%]; p < 0.05) and was relatively higher in lesions with nonmasslike enhancement (26/76 [34%]; p = 0.07), which represented ductal carcinoma in situ in the majority of cases (17/26 [65%]; p < 0.005). CONCLUSION: Patients with ipsilateral cancer who have additional suspicious lesions identified on MRI require careful evaluation and biopsy to exclude additional sites of cancer that may impact surgical management.
机译：目的：本文旨在将9线MRI指导的真空辅助乳腺活检与手术组织学检查结果相关联，以确定升级率，并将MRI指导的真空辅助的乳腺活检癌症诊断与乳腺MRI适应症相关和目标病变的增强特征。材料与方法：对2005年1月1日至2010年9月31日进行的所有MRI引导的真空辅助乳房活检进行了数据库搜索。乳房MRI适应症，病史，年龄，危险因素，病变大小，增强特征并记录了在MRI引导下的真空辅助乳腺活检和手术中的病理诊断。 Fisher精确检验和方差分析用于统计分析。结果：197例女性（平均年龄52岁;范围28-76岁）中共有218个病变接受了MRI引导的真空辅助乳房活检，其中85个（39％）具有手术相关性。根据MRI引导的真空辅助乳腺活检，在218个病变中，有48个（22％）为恶性，133个（61％）为良性，37个（17％）为高风险。 85个病灶中有10个（占12％）在手术时升级为恶性肿瘤，最终恶性率为25％。进行诊断（50/177 [28％]）的患者与进行筛查（4/41 [10％]; p <0.05），患侧癌的患者（22/49 [45％]）的恶性频率显着更高; p <0.001）和具有冲洗动力学的病变（34/103 [33％]; p <0.05），在非肿块状增强的病变中相对较高（26/76 [34％]; p = 0.07），代表导管大多数情况下为原位癌（17/26 [65％]; p <0.005）。结论：同侧癌症患者在MRI上发现其他可疑病变，需要仔细评估和活检，以排除可能影响手术管理的其他癌症部位。

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