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首页> 外文期刊>Heart, lung & circulation >Relationship Between Left Ventricle Position and Haemodynamic Parameters During Cardiopulmonary Resuscitation in a Pig Model
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Relationship Between Left Ventricle Position and Haemodynamic Parameters During Cardiopulmonary Resuscitation in a Pig Model

机译：猪模型中心肺复苏期间左心室位置与血管动力学参数的关系

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BackgroundFrom the viewpoint of cardiac pump theory, the area of the left ventricle (LV) subjected to compression increases as the LV lies closer to the sternum, possibly resulting in higher blood flow in patients with LV closer to the sternum. However, no study has evaluated LV position during cardiac arrest or its relationship with haemodynamic parameters during cardiopulmonary resuscitation (CPR). The objectives of this study were to determine whether the position of the LV relative to the anterior-posterior axis representing the direction of chest compression shifts during cardiac arrest and to examine the relationship between LV position and haemodynamic parameters during CPR. MethodsSubcostal view echocardiograms were obtained from 15 pigs with the transducer parallel to the long axis of the sternum before inducing ventricular fibrillation (VF) and during cardiac arrest. Computed tomography was performed in three pigs to objectively observe LV position during cardiac arrest. LV position parameters including the shortest distance between the anterior-posterior axis and the mid-point of the LV chamber (DAP-MidLV), the shortest distance between the anterior-posterior axis and the LV apex (DAP-Apex), and the area fraction of the LV located on the right side of the anterior-posterior axis (LVARight/LVATotal) were measured. ResultsDAP-MidLV, DAP-Apex, and LVARight/LVATotaldecreased progressively during untreated VF and basic life support (BLS), and then increased during advanced cardiovascular life support (ACLS). A repeated measures analysis of variance revealed significant time effects for these parameters. During BLS, the end-tidal carbon dioxide and systolic right atrial pressure were significantly correlated with the LV position parameters. During ACLS, systolic arterial pressure and systolic right atrial pressure were significantly correlated with DAP-MidLVand DAP-Apex. ConclusionsLeft ventricular position changed significantly during cardiac arrest compared to the pre-arrest baseline. LV position during CPR had significant correlations with haemodynamic parameters.
机译：背景从心脏泵理论的角度来看，受压缩的左心室（LV）的区域随着LV更接近胸骨，可能导致LV较近胸骨的患者血流。然而，在心脏骤停期间没有研究在心脏骤停期间评估了LV位置，或者在心肺复苏期间与血管动力学参数的关系进行了关系。该研究的目的是确定LV相对于前后轴的位置是否相对于表示心脏骤停期间的胸部压缩方向的前后轴线的位置，并在CPR期间检查LV位置和血流动力学参数之间的关系。方法在诱导心室纤维化（VF）和心脏骤停期间，从15猪从15只猪一起与胸骨的长轴平行于胸骨的换能器获得。在三头猪中进行了计算机断层扫描，客观地观察心脏骤停期间的LV位置。 LV位置参数，包括前后轴和LV室的中点（DAP-MIDLV）之间的最短距离，前后轴和LV顶点（DAP-APEX）之间的最短距离和区域测量位于前后轴（Lvaright / Lvatotal）的右侧的LV的级分。在未处理的VF和基本寿命支持（BLS）期间，结果表达-MIDLV，DAP-APEX和LVATOTALDecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdecrdect。在晚期心血管寿命支持（ACL）期间增加。反复措施的方差分析显示了这些参数的显着时间效应。在BLS期间，末端潮汐二氧化碳和收缩式右心房压力与LV位置参数显着相关。在ACL期间，收缩动脉压和收缩式右心房压力与DAP-MIDLVAND DAP-APEX显着相关。结论与预防基线相比，心脏骤停过程中的术间隙显着变化。 CPR期间的LV位置与血管动力学参数具有显着的相关性。

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