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首页> 外文期刊>Hormones and behavior >Association between maternal childhood maltreatment and mother-infant attachment disorganization: Moderation by maternal oxytocin receptor gene and cortisol secretion
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Association between maternal childhood maltreatment and mother-infant attachment disorganization: Moderation by maternal oxytocin receptor gene and cortisol secretion

机译：孕产妇儿童虐待和母婴附着紊乱之间的关联：母体催产素受体基因和皮质醇分泌的适度

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摘要

This study examined maternal oxytocin receptor (OXTR, rs53576) genotype and cortisol secretion as moderators of the relation between maternal childhood maltreatment history and disorganized mother-infant attachment in the Strange Situation Procedure (SSP). A community sample of 314 mother-infant dyads completed the SSP at infant age 17 months. Self-reported maltreatment history more strongly predicted mother-infant attachment disorganization score and disorganized classification for mothers with more plasticity alleles of OXTR (G), relative to mothers with fewer plasticity alleles. Maltreatment history also more strongly predicted mother-infant attachment disorganization score and classification for mothers with higher SSP cortisol secretion, relative to mothers with lower SSP cortisol secretion. Findings indicate that maltreatment history is related to disorganization in the next generation, but that this relation depends on maternal genetic characteristics and cortisol.
机译：本研究检测母体催产素受体（OXTR，RS53576）基因型和皮质醇分泌，作为陌生情况下的母体儿童虐待历史和混乱母婴附着的关系的主持人。 314名母婴二元的社区样本在17个月内完成了SSP。 自我报告的虐待历史更加强烈地预测母婴附着的分数和母亲的母亲对莫氏菌素（g）的塑性等位基因的混乱分类，相对于较少的塑性等位基因。 虐待历史也更加强烈地预测母婴附着的分解得分和母亲的分类，具有较高的SSP皮质醇分泌，相对于较低的SSP皮质醇分泌的母亲。 调查结果表明，虐待史与下一代中的紊乱有关，但这种关系取决于母体遗传特征和皮质醇。

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