Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

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Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

机译：成人促红细胞生成素给药指南对血液透析儿童促红细胞生成素的促进剂量，贫血和输血的影响：北美儿科肾脏试验和协作研究的研究结果（NAPRTCS）

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Background While adult hemodialysis (HD) patients have increased morbidity with higher target hemoglobin levels, similar findings have not been demonstrated in pediatric patients. We evaluated changes in transfusions, anemia frequency, and erythropoietin (epo) dosing among pediatric HD patients before, during, and after implementation of federal dialysis payment policies regarding epo dosing for adult HD patients.

机译：背景背景，虽然成年血液透析（HD）患者具有较高的目标血红蛋白水平的发病率升高，但在儿科患者中尚未证明类似的结果。我们在进一步，期间和之后评估了儿科高清患者的输血，贫血频率和促红细胞生成素（EPO）给药的变化，以后的成人高清患者的EPO给药的联邦透析支付政策。

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《Trends in Ecology & Evolution》 |2020年第2期|共7页
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正文语种 eng
中图分类数学生态学与生物模型;
关键词
Anemia; Hemodialysis; Erythropoietin; Transfusion; Children;

机译：贫血;血液透析;促红细胞生成素;输血;儿童;

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1. Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) [J] . Trends in Ecology & Evolution . 2020,第2期

机译：成人促红细胞生成素给药指南对血液透析儿童促红细胞生成素的促进剂量，贫血和输血的影响：北美儿科肾脏试验和协作研究的研究结果（NAPRTCS）
2. An open-label, multicenter, multiple-dose study to determine the optimum starting dose of CERA (continuous erythropoietin receptor activator - methoxy polyethylene glycol-epoetin beta) for maintenance treatment of anemia in pediatric patients with chronic kidney disease (CKD) on hemodialysis (HD) (NH19707, NCT00717366) [J] . Fischbach M., Wuehl E., Meyer-reigner S., Pediatric nephrology: journal of the International Pediatric Nephrology Association . 2016,第10期

机译：一项开放性，多中心，多剂量研究，用于确定CERA（连续性促红细胞生成素受体激活剂-甲氧基聚乙二醇-表皮素β）的最佳起始剂量，用于维持治疗慢性肾脏病（CKD）的小儿血液透析患者的贫血（ HD）（NH19707，NCT00717366）
3. Outcomes of kidney transplantation in children with nephronophthisis: an analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) Registry. [J] . Hamiwka LA, Midgley JP, Wade AW, Pediatric transplantation. . 2008,第8期

机译：肾病小儿肾脏移植的结果：对北美儿科肾脏试验和合作研究（NAPRTCS）注册中心的分析。
4. Reassessing Rabbit Antithymocyte Globulin Induction in Kidney Transplantation (RETHINK): An Analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) Registry [O] . Isa F. Ashoor, Karen Martz, Shirley Galbiati, 2020

机译：重新评估兔抗腹细胞球蛋白诱导肾移植（Rethink）：北美小儿肾试验分析及协作研究（NAPRTCS）注册表
5. A prospective cohort study of incident maintenance dialysis in children: An NAPRTC study11The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) is a voluntary collaborative effort comprising over 150 pediatric renal disease treatment centers in the United States, Canada, Mexico and Costa Rica. It is supported by major, unrestricted educational grants from Novartis, AMGEN, and Genentech. Participating NAPRTCS Centers are listed in the most recent NAPRTCS Annual Report Seikaly M, Ho PL, Emmet L, Tejani A: The 12th Annual Report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS): Renal Transplantation from 1987 through 1998. Pediatr Transplant 5:215–231, 2001. [O] . Leonard Mary B., Donaldson Lynn A., Ho Martin, 2003

机译：儿童事件维持性透析的前瞻性队列研究：NAPRTC研究11北美小儿肾脏移植合作研究（NAPRTCS）是一项自愿合作，由美国，加拿大，墨西哥和哥斯达黎加的150多个小儿肾脏疾病治疗中心组成。它得到了诺华，AMGEN和Genentech的重大无限制教育资助的支持。最新的NAPRTCS年度报告中列出了参与的NAPRTCS中心Seikaly M，Ho PL，Emmet L，Tejani A：《北美小儿肾脏移植合作研究》（NAPRTCS）第12份年度报告：1987年至1998年的肾脏移植。Pediatr移植5：215-231，2001。

Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

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