A source of great personal suffering and societal burden, neuropsychiatric disease affects all people throughout the world. One hundred and fifty-one million individuals glob-ally have depression, and nearly half (46%) of the people in the United States will experience an episode of mental ill-ness during the course of their lives (WHO 2010). By 2020, mental illness will be the second leading cause of death and disability (Mitchell 2005), and by 2025, there will be roughly 34 million people living with Alzheimer 's disease and other forms of dementia (Alzheimer's Society 2011; WHO 2010). Mental illness among young people is prevalent, and sui-cide is presently the third leading cause of death in ado-lescence and early adulthood (American Foundation for Suicide Prevention 2011; Centers for Disease Control and Prevention 2011). Co-occurring conditions, such as sub-stance dependence, intellectual disability, and medically complex diseases, are becoming usual rather than rare (Conway et al. 2006; Regier et al. 1990; U.S. Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse 2010). All of these pat-terns are worrisomely heightened in specific subpopula-tions, such as among indigenous peoples, rural elders and adolescents, the incarcerated, some military personnel and veterans, recent immigrants, and the very old (National In-stitute of Mental Health 2002; 2004; 2010; Centers for Disease Control and Prevention 2011; Suicide Prevention Task Force 2010). And, by any measure, access to adequate health care services for neuropsychiatric diseases simply does not exist, even in economically established countries (The Common-wealth Fund 2011; World Health Organization 2011).
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机译：神经精神疾病是巨大的个人痛苦和社会负担的根源，它影响着全世界的所有人。全球有1.51亿人患有抑郁症，在美国，将近一半（46％）的人在生活中会经历精神疾病发作（WHO 2010）。到2020年，精神疾病将成为导致死亡和残疾的第二大原因（Mitchell 2005），到2025年，将有大约3400万人患有阿尔茨海默氏病和其他形式的痴呆症（Alzheimer's Society 2011; WHO 2010） 。年轻人中的精神疾病很普遍，而自杀是目前处于衰老和成年早期的第三大死亡原因（美国自杀预防基金会，2011;疾病控制与预防中心，2011）。共同出现的疾病，例如物质依赖，智力残疾和医学上复杂的疾病，正在变得常见而不是罕见（Conway等，2006; Regier等，1990;美国卫生与公共服务部，美国国立卫生研究院）。卫生，国家药物滥用研究所，2010年）。所有这些模式在特定的亚人群中都令人担忧地提高，例如在土著人民，农村老年人和青少年，被监禁的人，一些军事人员和退伍军人，新移民以及非常老的人群中（国家精神卫生研究所2002年; 2004年; 2010年;疾病预防控制中心，2011年;自杀预防工作组，2010年）。而且，无论如何，即使在经济发达的国家中，也根本不存在针对神经精神疾病提供适当医疗服务的机会（英联邦基金，2011;世界卫生组织，2011）。
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