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Next generation radiologic-pathologic correlation in oncology: Rad-Path 2.0.

机译:肿瘤学中的下一代放射病理学相关性:Rad-Path 2.0。

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摘要

OBJECTIVE: The bedrock of radiology has been radiologic-pathologic (Rad-Path) correlation: the correlation of imaging to ex vivo gross and histopathologic findings of disease. This classical view is being challenged by our increasing understanding of the molecular basis of disease, particularly in oncology. The traditional lines in diagnostic sciences have blurred with the development of new in vitro diagnostic molecular assays and molecular imaging methods as well as the growing evidence that conventional diagnostic imaging has potential use in understanding genomic properties of disease. The purpose of this article is to make the case for a fundamental shift to the next generation of Rad-Path correlation (Rad-Path 2.0). CONCLUSION: The future success of radiology will require not only continued technologic advances in physical and life sciences but also the convergence of previously distinct diagnostic disciplines.
机译:目的:放射学的基石一直是放射病理学(Rad-Path)相关性:影像学与疾病的离体总体和组织病理学发现之间的相关性。我们对疾病,尤其是肿瘤学的分子基础的日益了解,正挑战着这种经典观点。随着新的体外诊断分子测定法和分子成像方法的发展,以及越来越多的证据表明常规诊断成像可用于理解疾病的基因组特性,诊断科学中的传统方法已变得模糊。本文的目的是为从根本上过渡到下一代Rad-Path相关(Rad-Path 2.0)提供理由。结论:放射学的未来成功将不仅需要物理和生命科学领域的持续技术进步,而且还需要融合先前截然不同的诊断学科。

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