• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Adenosine-stress dynamic myocardial perfusion imaging with second-generation dual-source CT: Comparison with conventional catheter coronary angiography and SPECT nuclear myocardial perfusion imaging
【24h】

Adenosine-stress dynamic myocardial perfusion imaging with second-generation dual-source CT: Comparison with conventional catheter coronary angiography and SPECT nuclear myocardial perfusion imaging

机译：第二代双源CT腺苷应力动态心肌灌注显像：与常规导管冠状动脉造影和SPECT核心肌灌注显像的比较

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE. The purpose of this article is to evaluate the feasibility of adenosine-stress dynamic myocardial perfusion imaging (MPI) with 128-MDCT dual-source CT for detecting myocardial ischemia in comparison with conventional catheter coronary angiography and nuclear MPI. SUBJECTS AND METHODS. Thirty patients (21 men and nine women; mean [± SD] age, 59.2 ± 7.6 years) prospectively underwent a combined stress CT perfusion and CT angiography (CTA) examination. Complete time-attenuation curves of the myocardium were acquired with prospectively ECG-triggered axial images at two alternating positions. Myocardial blood flow (MBF) was quantified according to dynamic CT perfusion, and MBF values of normal and abnormal segments were compared. Findings on CT perfusion were compared with those for stress and rest SPECT. Perfusion defects according to CT were correlated to flow-obstructing stenosis detected on CTA and catheter coronary angiography. RESULTS. On stress CT perfusion, 19 patients (63%) and 83 of 504 segments (16%) had perfusion abnormalities. There was a significant difference in MBF values between normal (142.9 ±30.6 mL/100 mL/min) and hypoperfused (90.0 ± 22.8 mL/100 mL/min) segments (p < 0.001). With nuclear MPI results as a comparison, the sensitivity, specificity, positive predictive value, and negative predictive value of CT perfusion for identifying segments with perfusion defects were 0.85, 0.92, 0.55, and 0.98, respectively. On a per-vessel basis, sensitivity, specificity, positive predictive value, and negative predictive value for detecting flow-obstructing stenosis were, respectively, 1.00, 0.757, 0.541, and 1.00 for CT perfusion; 0.90, 0.514, 0.346, and 0.947 for CTA; and 0.90, 0.814, 0.581, and 0.966 for CT perfusion combined with CTA. CONCLUSION. Adenosine-stress CT perfusion detects myocardial perfusion defects in good correlation with nuclear MPI. CT perfusion combined with CTA improves the diagnostic accuracy for identifying flow-obstructing stenosis compared with CTA alone.
机译：目的。本文的目的是评估与常规导管冠状动脉造影和核MPI相比，使用128-MDCT双源CT进行腺苷应力动态心肌灌注成像（MPI）来检测心肌缺血的可行性。主题和方法。预期对30例患者（21例男性和9例女性;平均[±SD]年龄，59.2±7.6岁）进行了应力CT灌注和CT血管造影（CTA）检查。使用前瞻性心电图触发的轴向图像在两个交替的位置获取了完整的心肌时间衰减曲线。根据动态CT灌注定量心肌血流量（MBF），并比较正常和异常节段的MBF值。将CT灌注结果与压力和静息SPECT结果进行比较。根据CT的灌注缺陷与在CTA和导管冠状动脉造影上发现的血流狭窄相关。结果。在压力CT灌注下，19例患者（63％）和504个节段中的83例（16％）出现灌注异常。正常（142.9±30.6 mL / 100 mL / min）和灌注不足（90.0±22.8 mL / 100 mL / min）段之间的MBF值存在显着差异（p <0.001）。与核MPI结果进行比较，CT灌注用于识别具有灌注缺陷的节段的敏感性，特异性，阳性预测值和阴性预测值分别为0.85、0.92、0.55和0.98。以每支血管为基础，CT灌注检测狭窄的敏感性，特异性，阳性预测值和阴性预测值分别为1.00、0.757、0.541和1.00; CTA为0.90、0.514、0.346和0.947; CT灌注结合CTA分别为0.90、0.814、0.581和0.966。结论。腺苷应力CT灌注检测到的心肌灌注缺陷与核MPI密切相关。与单独使用CTA相比，CT灌注结合CTA可以提高诊断准确性，以识别阻塞血流的狭窄。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号