...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >1H MR spectroscopy and diffusion-weighted imaging of the breast: are they useful tools for characterizing breast lesions before biopsy?
【24h】

1H MR spectroscopy and diffusion-weighted imaging of the breast: are they useful tools for characterizing breast lesions before biopsy?

机译：1H MR光谱和乳腺弥散加权成像：它们在活检前表征乳腺病变有用吗？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: The objective of our study was to determine whether proton ((1)H) MR spectroscopy (MRS) and diffusion-weighted imaging might be useful tools for characterizing breast lesions before biopsy. MATERIALS AND METHODS: Single-voxel (1)H MRS and diffusion-weighted imaging were performed in 171 suspicious or highly suspicious lesions. Using the residual water signal as a reference (4.7 ppm), a choline peak at 3.22-3.23 ppm was defined as malignant. If a high-signal-intensity lesion was detected in high-b-value (b = 1,500 s/mm(2)) images, that lesion was defined as positive for malignancy. Among the patients with positive results on diffusion-weighted imaging, the apparent diffusion coefficient (ADC) values of the mass or focus were calculated from two different gradient factors (b(1) = 500 s/mm(2) and b(2) = 1,500 s/mm(2)). RESULTS: The diagnostic sensitivity and specificity of (1)H MRS were 44% (40/91) and 85% (68/80), respectively (p < 0.001). If (1)H MRS was applied for mass lesions larger than 15 mm, the diagnostic sensitivity and specificity were 82% (28/34) and 69% (11/16), respectively. Of the high-b-value images, 24 benign lesions and eight nonmass ductal carcinoma in situ were visually negative. With the use of a cutoff ADC value of 1.13 x 10(-3) mm(2)/s, a specificity of 67% (43/64) and sensitivity of 97% (61/63) was obtained on diffusion-weighted imaging. CONCLUSION: (1)H MRS was useful for characterizing breast lesions measuring 15 mm or larger, and diffusion-weighted imaging was useful for characterizing lesions of any size. However, these two techniques still have potential pitfalls in relation to the diagnosis of nonmass breast lesions.
机译：目的：我们的研究目的是确定质子（（1）H）磁共振波谱（MRS）和弥散加权成像是否可能是活检前表征乳腺病变的有用工具。材料与方法：对171个可疑或高度可疑的病变进行了单素（1）H MRS和弥散加权成像。使用残留水信号作为参考（4.7 ppm），将胆碱在3​​.22-3.23 ppm处的峰定义为恶性。如果在高b值（b = 1,500 s / mm（2））图像中检测到高信号强度病变，则该病变被定义为恶性阳性。在弥散加权成像阳性结果的患者中，从两个不同的梯度因子（b（1）= 500 s / mm（2）和b（2） = 1,500 s / mm（2））。结果：（1）H MRS的诊断敏感性和特异性分别为44％（40/91）和85％（68/80）（p <0.001）。如果将（1）H MRS应用于大于15 mm的肿块，诊断敏感性和特异性分别为82％（28/34）和69％（11/16）。在高b值图像中，有24例良性病变和8例原位非肿块导管癌均为视觉阴性。使用1.13 x 10（-3）mm（2）/ s的截止ADC值，在扩散加权成像中获得67％（43/64）的特异性和97％（61/63）的灵敏度。结论：（1）H MRS可用于表征15 mm或更大的乳腺病变，扩散加权成像可用于表征任何大小的病变。但是，这两种技术在诊断乳腺无肿块方面仍然存在潜在的陷阱。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号