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Current issues and perspectives in food safety and risk assessment

机译:食品安全和风险评估中的当前问题和视角

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摘要

In this review, current issues and opportunities in food safety assessment are discussed. Food safety is considered an essential element inherent in global food security. Hazard characterization is pivotal within the continuum of risk assessment, but it may be conceived only within a very limited frame as a true alternative to risk assessment. Elucidation of the mode of action underlying a given hazard is vital to create a plausible basis for human toxicology evaluation. Risk assessment, to convey meaningful risk communication, must be based on appropriate and reliable consideration of both exposure and mode of action. New perspectives, provided by monitoring human exogenous and endogenous exposure biomarkers, are considered of great promise to support classical risk extrapolation from animal toxicology.
机译:在本综述中,讨论了当前的食品安全评估问题和机会。 食品安全被认为是全球粮食安全固有的基本要素。 危险表征在风险评估中的连续内是关键,但它只可以在一个非常有限的框架内认为是风险评估的真实替代品。 阐明给定危害的行动方式至关重要为为人类毒理学评估创造合理的基础。 风险评估,传达有意义的风险沟通,必须基于适当可靠的曝光和行动方式的考虑。 通过监测人类外源性和内源性暴露生物标志物提供的新观点被认为是从动物毒理学中支持古典风险推断的巨大希望。

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