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首页> 外文期刊>Magnetic resonance imaging: An International journal of basic research and clinical applications >A robust SSFP technique for fMRI at ultra-high field strengths
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A robust SSFP technique for fMRI at ultra-high field strengths

机译：超高场强的FMRI强大的SSFP技术

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摘要

A non-balanced (nb) SSFP-based fMRI method based on CE-FAST is presented to alleviate some shortcomings of high spatial-specificity techniques commonly used in high static magnetic fields. The proposed sequence does not suffer from the banding artifacts inherent to balanced (b) SSFP, has low geometrical distortions and SAR compared to spin-echo EPI, and in contrast to previous nbSSFP implementations, is applied at a TR, theoretically prescribed for the optimum contrast. Its non-balanced gradient was chosen to just dephase the unwanted signal component (2 pi dephasing per TR per voxel). 3D data were acquired from nine healthy subjects, who performed a visual-motor task on a 7 Tesla scanner. For comparison, experiments were accompanied by similar bSSFP and spin-echo acquisitions. Consistent activation was achieved in all subjects with theoretically optimal TR, in contrast to previous nbSSFP techniques. The signal stability as well as relative and absolute functional signal changes, were found to be comparable with bSSFP and spin-echo techniques. The results suggest that with suitable modifications, CE-FAST can be regarded as a robust SSFP-based method for high spatial specificity fMRI techniques.
机译：提出了一种基于CE-FATE的基于基于CE-FATE的基于SSFP的FMRI方法，以减轻通常用于高静态磁场中的高空间特异性技术的一些缺点。所提出的序列不会遭受平衡（b）SSFP固有的带状伪影，与旋转回波EPI相比，与先前的NBSSFP实现相比，具有低几何失真和SAR，其在理论上施加到最佳的TR，理论上规定对比。选择其非平衡梯度仅选中不需要的信号分量（每个voxel每个Tr）。 3D数据从九个健康受试者获取，他们在7个Tesla扫描仪上执行了视觉电机任务。为了比较，实验伴随着类似的BSSFP和旋转回波采集。与先前的NBSSFP技术相比，在理论上最佳Tr的所有受试者中实现了一致的活化。发现信号稳定性以及相对和绝对的功能信号变化，与BSSFP和旋转回波技术相当。结果表明，通过适当的修改，CE-FAST可以被视为基于鲁棒的SSFP的方法，用于高空间特异性FMRI技术。

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