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首页> 外文期刊>Dermatitis: contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group >Dubiously Doubtful: An Exploration of the Literature Concerning Doubtful, Macular Erythema, '? plus ,' and ' plus /-' Patch Test Reactions
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Dubiously Doubtful: An Exploration of the Literature Concerning Doubtful, Macular Erythema, '? plus ,' and ' plus /-' Patch Test Reactions

机译：安全令人怀疑：探索令人怀疑，黄斑红斑，“？加”和“加上/ - ”补丁测试反应的探索

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摘要

When the final patch test reading is barely discernable, it is termed a doubtful, macular erythema, "?+," or "+/-" reaction (hereby referred to as doubtful reaction). Information is conflicting about how to interpret doubtful reactions. Many guidelines do not comment on how to approach doubtful reactions; others state that further evaluation can (not should) be performed. In clinical reports, some investigators regard them as positive allergic reactions; some, as positive under certain circumstances; and many, as negative. Indeed, 16 (84%) of 19 recent reports of patch test reactions to standard/baseline series considered doubtful reactions negative for purposes of the report and did not include the number of these reactions. The problem is that these reactions are common and are not infrequently relevant. We recommend that researchers include frequency of doubtful reactions in reports and that doubtful reactions be assessed with the same scrutiny as stronger allergic reactions in the clinical setting.
机译：当最终贴剂测试读数勉强可辨别时，它被称为怀疑，黄斑红斑，“？+，”或“+/-”反应（在此称为可疑的反应）。信息与如何解释怀疑的反应相互矛盾。许多指导方针没有评论如何接受可疑的反应;其他人说进一步评估可以（不应该）进行。在临床报告中，一些调查人员将它们视为阳性过敏反应;一些，在某些情况下是积极的;很多，是消极的。实际上，16（84％）的19个近期报告对标准/基线系列的补丁测试反应报告认为是报告目的的怀疑反应，并且不包括这些反应的数量。问题是这些反应是常见的，并且不是不经常相关的。我们建议研究人员包括报告中可疑反应的频率，并且在临床环境中具有与更强的过敏反应相同的审查评估。

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