Automated HEK293 suspension cell adaptation to new media and use of new DoE approach to optimize AAV production in suspension utilizing the ambr (R) 15 platform

Robin C.; Enga M.; Menard L.; Pennors M.; Blouin V.; Adjali O.; Houyoux V.; Zuban R.; Vicard Q.; Ayuso E.

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Automated HEK293 suspension cell adaptation to new media and use of new DoE approach to optimize AAV production in suspension utilizing the ambr (R) 15 platform

机译：自动HEK293悬浮电池适应新媒体和使用新的DOE方法，利用AMBR（R）15平台在悬架中优化AAV生产

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来源
《Human gene therapy》 |2019年第11期|共1页
作者
Robin C.; Enga M.; Menard L.; Pennors M.; Blouin V.; Adjali O.; Houyoux V.; Zuban R.; Vicard Q.; Ayuso E.;
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作者单位

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

Sartorius Stedim Biotech Aubagne France;

Sartorius Stedim Biotech Aubagne France;

Sartorius Stedim Biotech Aubagne France;

Univ Nantes CHU Nantes INSERM UMR1089 Nantes France;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
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专利

1. Automated HEK293 suspension cell adaptation to new media and use of new DoE approach to optimize AAV production in suspension utilizing the ambr (R) 15 platform [J] . Robin C., Enga M., Menard L., Human gene therapy . 2019,第11期

机译：自动HEK293悬浮电池适应新媒体和使用新的DOE方法，利用AMBR（R）15平台在悬架中优化AAV生产
2. Creation of a High-Yield AAV Vector Production Platform in Suspension Cells Using a Design-of-Experiment Approach [J] . Huiren Zhao, Ki-Jeong Lee, Mark Daris, Molecular Therapy - Methods & Clinical Development . 2020,第3期

机译：使用实验设计方法在悬浮电池中创建高产AAV矢量生产平台
3. Evaluation of a new chemically defined medium for production of AAV vectors by transient transfection of suspension HEK293 cells in stirred tank bioreactors [J] . Guianvarch L., Boussicault F., Dufour D., Human gene therapy . 2016,第11期

机译：通过在搅拌槽生物反应器中悬浮HEK293细胞的瞬时转染来评估用于AAV载体生产的新化学定义培养基
4. OPTIMIZATION OF HEK293T SUSPENSION CULTIVATION WITH A DoE-APPROACH IN ambr®15 MICROBIOREACTOR [C] . Franziska Bollmann, Diana Riethmueller, Erik Johansson, Conference on advancing manufacture of cell and gene therapies . 2019

机译：用doe方法在ambr®15微生物反应器中优化HEK293T悬浮培养
5. Development of plant cell suspension cultures as a bioproduction platform for recombinant human therapeutic proteins [D] . Huang, Ting-Kuo 2009

机译：开发植物细胞悬浮培养物作为重组人治疗性蛋白质的生物生产平台
6. Media optimization for CHO fed-batch processes using a DoE approach in automated high-throughput single use ambr15 bioreactors [O] . Christophe Grimm, Wolfgang Kusser, Brian Lee, 2015

机译：使用DoE方法在自动化高通量单次使用ambr15生物反应器中进行CHO补料分批工艺的培养基优化
7. Media optimization for CHO fed-batch processes using a DoE approach in automated high-throughput single use ambr15 bioreactors [O] . 2015

机译：使用DoE方法在自动化高通量单次使用ambr15生物反应器中进行CHO补料分批工艺的培养基优化

Automated HEK293 suspension cell adaptation to new media and use of new DoE approach to optimize AAV production in suspension utilizing the ambr (R) 15 platform

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