...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Diagnostic cytopathology >Serum calcitonin negative mixed medullary‐follicular carcinoma initially diagnosed as medullary thyroid carcinoma by fine‐needle aspiration cytology: A case report and review of the literatures
【24h】

Serum calcitonin negative mixed medullary‐follicular carcinoma initially diagnosed as medullary thyroid carcinoma by fine‐needle aspiration cytology: A case report and review of the literatures

机译：血清降钙素阴性混合髓质卵状癌最初通过细针穿刺细胞学被诊断为髓质甲状腺癌：对文献的报告和审查

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Medullary thyroid carcinoma (MTC) is potentially lethal. A prompt and accurate diagnosis is the prerequisite for the treatment of MTC. Fine‐needle aspiration (FNA) is a reliable diagnostic tool in the assessment of thyroid nodules. However, cytologic assessment of MTC based on FNA has several drawbacks due to morphological variants. We present a case of MTC diagnosed through FNA cytology, which was eventually histologically confirmed as a mixed medullary‐follicular carcinoma with negative serum calcitonin expression. Hence, diagnosis of MTC based on FNA should be applied with caution. Ultrasound characteristics of suspicious thyroid nodules are recommended to be evaluated by FNA. However, calcitonin levels should be measured in both the FNA washout fluid and serum when features of MTC are presented or cytology result is inconclusive. If adequate FNA sample is available, a supplementary immunocytochemical staining of markers such as calcitonin, chromogranin, carcinoembryonic antigen, and thyroglobulin is helpful for a correct diagnosis of MTC.
机译：髓质甲状腺癌（MTC）可能是致命的。提示和准确的诊断是治疗MTC的先决条件。细针抽吸（FNA）是评估甲状腺结节的可靠诊断工具。然而，基于FNA的MTC对MTC的细胞学评估具有由于形态学变异的几个缺点。我们提出了通过FNA细胞学诊断的MTC的情况，其最终组织学证实为具有负血清降钙素表达的混合髓质卵泡癌。因此，应谨慎施用基于FNA的MTC的诊断。建议通过FNA评估可疑甲状腺结节的超声特性。然而，当呈现MTC的特征或细胞学结果时，应在FNA冲洗液和血清中测量降钙素水平，或者细胞学结果不确定。如果可获得足够的FNA样品，则辅助免疫细胞化学染色如降钙素，Chromogranin，癌症丙烯抗原和甲状腺蛋白是有助于对MTC的正确诊断。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号