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首页> 外文期刊>Alcohol >A comparison of neurocognitive function in nonsmoking and chronically smoking short-term abstinent alcoholics.
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A comparison of neurocognitive function in nonsmoking and chronically smoking short-term abstinent alcoholics.

机译：非吸烟和长期吸烟短期戒酒者神经认知功能的比较。

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Approximately 70-90% of individuals in North America seeking treatment for alcoholism are chronic smokers. A growing body of evidence suggests chronic cigarette smoking alone adversely affects neurocognition in adults. However, few studies on the neurocognitive function of short-term abstinent alcoholics have specifically considered the potential effects of chronic cigarette smoking. In this study, 20 nonsmoking recovering alcoholics (nsRA) and 22 actively smoking recovering alcoholics (sRA) participants, matched on age and education, were contrasted on a comprehensive neurocognitive battery after 34+/-9 days of abstinence. nsRA were superior to sRA on measures of auditory-verbal learning and memory, processing speed, cognitive efficiency, and static postural stability. These group differences were not a function of group disparities in age, education, estimated premorbid verbal intelligence, lifetime alcohol consumption, or other measured comorbid psychiatric or medical factors. In sRA, longer smokingduration was negatively correlated with executive skills, visuospatial learning, general cognitive efficiency, and static postural stability. These results indicate that greater consideration of the potential neurobiological effects of current chronic smoking on neurocognitive functioning is warranted in studies of alcoholism and other conditions where smoking is a common comorbid factor.
机译：在北美寻求戒酒治疗的人中，大约70-90％是长期吸烟者。越来越多的证据表明，仅长期吸烟会对成年人的神经认知产生不利影响。但是，很少有关于短期戒酒者神经认知功能的研究专门考虑慢性吸烟的潜在影响。在这项研究中，在禁酒期34 +/- 9天后，根据年龄和文化程度对20名非吸烟恢复性酒精中毒（nsRA）和22名积极吸烟恢复性酒精中毒（sRA）参与者进行了全面的神经认知训练。在听觉语言学习和记忆，处理速度，认知效率和静态姿势稳定性方面，nsRA优于sRA。这些群体差异不是年龄，教育程度，估计的病前言语智能，终生饮酒或其他衡量的合并精神病或医学因素导致的群体差异的函数。在sRA中，更长的吸烟时间与执行技能，视觉空间学习，总体认知效率和静态姿势稳定性呈负相关。这些结果表明，在酗酒和吸烟为常见合并症的其他疾病研究中，有必要更深入地考虑当前慢性吸烟对神经认知功能的潜在神经生物学作用。

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