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首页> 外文期刊>Digestive Diseases and Sciences >Clinical Outcomes of Patients with Non-ulcer and Non-variceal Upper Gastrointestinal Bleeding: A Prospective Multicenter Study of Risk Prediction Using a Scoring System
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Clinical Outcomes of Patients with Non-ulcer and Non-variceal Upper Gastrointestinal Bleeding: A Prospective Multicenter Study of Risk Prediction Using a Scoring System

机译：非溃疡性和非变性上胃肠道出血患者的临床结果：使用评分系统进行风险预测的前瞻性多中心研究

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Background and AimsCompared with ulcer bleeding (UB) in non-variceal upper gastrointestinal bleeding (NVUGIB), non-ulcer bleeding (NUB) is often considered to have a low risk of poor outcomes and is treated less intensively without any risk stratification. We conducted this study to assess the predictability of scoring systems for NUB and compare the outcomes of NUB and UB.MethodsA total of 1831 UGIB patients were registered in the database during the period from February 2011 to December 2013. Among them, 1424 patients with NVUGIB were divided into two groups: Group UB (1101 patients with peptic ulcer bleeding) and Group NUB (323 patients with non-peptic ulcer-related bleeding).ResultsThe most common cause of bleeding in Group NUB was Mallory-Weiss tears (51.1%), followed by Dieulafoy lesions (18.9%). A receiver operating characteristic (ROC) analysis revealed that the pre-Rockall score [area under the ROC (AUROC)=0.798; 95% CI 0.707-0.890] and full Rockall score (AUROC=0.794; 95% CI 0.693-0.895) were relatively good at predicting overall mortality in NUB. Glasgow-Blatchford score (AUROC=0.783; 95% CI 0.730-0.836) was the most closely correlated with the need for clinical intervention in NUB. Those who had Glasgow-Blatchford score of 0 did not require any interventions, including blood transfusions. There were no statistical differences in overall mortality (p=0.387), bleeding-related mortality (p=0.447), or the incidence of re-bleeding (p=0.117) between the two groups.ConclusionsScoring systems are useful to predict mortality and the need for clinical intervention in patients with NUB.
机译：背景和Aimscombered在非变质上胃肠道出血（NVUGIB）中的溃疡出血（UB），通常认为非溃疡出血（NUB）具有低差的成果的风险，并且在没有任何风险分层的情况下较少处理。我们进行了本研究，评估了Nub评分系统的可预测性，并比较Nub和Ub的结果。在2011年2月至2013年2月的期间，在数据库中注册了1831名Ugib患者。其中，1424例NVUGIB患者分为两组：组UB（1101例患有消化性溃疡出血患者）和组NUB（323名非消化性溃疡相关出血的患者）.Resultthe群体中出血的最常见原因是Mallory-Weiss泪水（51.1％） ，其次是Dieulafoy病变（18.9％）。接收器操作特征（ROC）分析表明，ROCKALL评分[ROC（AUROC）下的面积= 0.798; 95％CI 0.707-0.890]和全隆起评分（AUROC = 0.794; 95％CI 0.693-0.895）在预测NUB中的总体死亡率相对较好。 Glasgow-Blatchford得分（Auroc = 0.783; 95％CI 0.730-0.836）是最密切相关的，与NUB中的临床干预需要最密切相关。那些有Glasgow-Blatchford得分0的人不需要任何干预措施，包括输血。总体死亡率没有统计学差异（p = 0.387），出血相关的死亡率（p = 0.447），或两组之间的再出血（p = 0.117）的发生率。结肠系统锻射系统可用于预测死亡率和需要NUB患者的临床干预。

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