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Redox potential control and applications in microaerobic and anaerobic fermentations

机译:氧化还原电位控制及其在微好氧和厌氧发酵中的应用

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摘要

Many fermentation products are produced under microaerobic or anaerobic conditions, in which oxygen is undetectable by dissolved oxygen probe, presenting a challenge for process monitoring and control. Extracellular redox potentials that can be detected conveniently affect intracellular redox homeostasis and metabolism, and consequently control profiles of fermentation products, which provide an alternative for monitoring and control of these fermentation processes. This article reviews updated progress in the impact of redox potentials on gene expression, protein biosynthesis and metabolism as well as redox potential control strategies for more efficient production of fermentation products, taking ethanol fermentation by the yeast Saccharomyces under microaerobic conditions and butanol production by the bacterium Clostridium under anaerobic conditions as examples
机译:许多发酵产品是在微需氧或厌氧条件下生产的,在这些条件下,溶解氧探针无法检测到氧气,这对过程的监测和控制提出了挑战。可以方便地检测到的细胞外氧化还原电位会影响细胞内氧化还原的稳态和代谢,从而控制发酵产物的分布,为监测和控制这些发酵过程提供了另一种选择。本文回顾了氧化还原电势对基因表达,蛋白质生物合成和代谢以及氧化还原电势控制策略的最新进展,以更有效地生产发酵产品,在微好氧条件下采用酵母菌进行乙醇发酵,并通过细菌生产丁醇。厌氧条件下的梭菌

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