...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biotechnology Advances: An International Review Journal >Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production [Review]
【24h】

Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production [Review]

机译：云芝科的多糖糖肽：生理活性，用途和生产[综述]

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The protein-bound polysaccharides or polysaccharopeptides produced by Coriolus versicolor are effective immunopotentiators, which are used to supplement the chemotherapy and radiotherapy of cancers and various infectious diseases. Antitumor activity of polysaccharopeptides,has been documented. Several kinds of protein-bound polysaccharides have been shown to be produced by the white rot fungus, C. versicolor. Although some of these polymers are structurally distinct, they are not distinguishable in terms of their physiological activity. This review focuses on the physiologically active polysaccharopeptides of C. versicolor. In nature, C. versicolor occurs as a mushroom body, but the fungus can be grown as mycelial biomass in submerged culture in bioreactors. Mushrooms gathered in the wild, cultivated mushrooms, and the mycelial biomass of submerged culture are used to produce the polysaccharopeptides. Submerged cultures are typically carried out in batches lasting 5-7 days and at 25-27 degreesC. Hot water extraction of the biomass is used to recover the thermostable polysaccharopeptides that are concentrated, purified, and dried into a powder for medicinal use. In. view of the documented physiological benefits of these compounds, extensive research is underway on the structure, composition, production methods, and use of new C. versicolor strains for producing the therapeutic biopolymers. Properties, physiological activity, recovery, and purification of the bioactive polysaccharopeptides are discussed.
机译：科里奥蓝藻生产的与蛋白质结合的多糖或多糖肽是有效的免疫增强剂，可用于补充癌症和各种传染病的化学疗法和放射疗法。多糖肽的抗肿瘤活性已有文献记载。已显示白腐真菌C. versicolor可产生几种与蛋白质结合的多糖。尽管这些聚合物中的一些在结构上是不同的，但是就其生理活性而言，它们是不可区分的。这篇综述着重于杂色衣藻的生理活性多糖肽。在自然界中，杂色衣原体（C. versicolor）以蘑菇体的形式出现，但真菌可以在生物反应器中的水下培养中作为菌丝体生物质生长。蘑菇收集在野生的，栽培的蘑菇中，而淹没培养的菌丝生物量则用于生产多糖肽。浸没培养通常在25-27摄氏度下分批进行，持续5-7天。生物质的热水提取用于回收热稳定的多糖肽，将其浓缩，纯化并干燥成粉末以供药用。在。考虑到这些化合物的文献记载的生理益处，正在进行有关结构，组成，生产方法以及使用新的杂色梭菌菌株生产治疗性生物聚合物的广泛研究。讨论了生物活性多糖肽的性质，生理活性，回收和纯化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号