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Image Quiz:What do you seein this cytology slide?

机译:图像测验:你看到这种细胞学的幻灯片是什么?

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This image shows the skin cytology of a sample from the dorsal trunk of an 8-year-old male neutered golden retriever. What's your diagnosis?a. Acantholytic cells,b. Agranular mast cells,c. Atypical lymphocytes,d. Fibroblasts Image quiz correct answer is C. Atypical lymphocytes.This dog was diagnosed with cutaneous lymphoma. These atypical lymphocytes are characterized by large round cells that have minimal cytoplasm and large deeply basophilic nuclei with finely stippled chromatin. Often the nuclei aremore centrally placed compared with macrophages and will not have an activated "foamy" appearance. They are mostly seen in large clusters and not individually. Occasionally many neutrophils will be present around them as well. They are an indication to biopsy the skin to further confirm lymphoma.
机译:该图像显示了来自8岁男性绝育的金毛猎犬的背部躯干的样本的皮肤细胞学。 你的诊断是什么? 反应性细胞,b。 八卦肥大细胞,c。 非典型淋巴细胞,d。 成纤维细胞图像测验正确答案是C.非典型淋巴细胞。本狗被诊断为皮肤淋巴瘤。 这些非典型淋巴细胞的特征在于大圆形细胞,其具有最小的细胞质和大的深层嗜碱性核,其具有精细染色的染色质。 通常,核心常见的核心与巨噬细胞相比,不会有活化的“泡沫状”外观。 它们主要在大集群中看到而不是单独的。 偶尔也会在他们周围存在许多中性粒细胞。 它们是一种活检肌肤,以进一步确认淋巴瘤。

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