Characterization and in vitro Cytotoxicity Evaluation of Meloxicam Loaded PEGylated Mixed Micelles Fabricated Using Quality by Design Approach

Jessy Shaji Ipshita Menon

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Characterization and in vitro Cytotoxicity Evaluation of Meloxicam Loaded PEGylated Mixed Micelles Fabricated Using Quality by Design Approach

机译：通过设计方法使用质量制造美洛昔康载荷的聚乙二醇化混合胶束的表征和体外细胞毒性评价

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Background: Colorectal cancer claims the life of millions of people globally. Chemopre-vention is among the upcoming approaches for the treatment of colorectal cancer. It involves the use of therapeutic agents which are essentially not cytotoxic drugs but, however, impedes the carcinogenesis. Meloxicam (MLX) is one such agent which has the potential to be employed in the chemopreventive therapy of colorectal cancer. The aim of this study was to formulate MLX into a formulation so as to exploit its potential to the fullest.

机译：背景：结肠直肠癌声称全球数百万人的生命。 Chemopre-VINET是治疗结直肠癌的即将到来的方法。它涉及使用基本上不是细胞毒性药物的治疗剂，但是，阻碍了致癌作用。 Meloxicam（MLX）是一种这样的试剂，其具有在结直肠癌的化学预防治疗中使用的可能性。本研究的目的是将MLX标准化成制剂，以便利用其充分利用。

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来源
《Drug delivery letters》 |2015年第3期|共13页
作者
Jessy Shaji Ipshita Menon;
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作者单位

Principal K.M. Kundnani College of Pharmacy 23 Jote Joy Building Rambhau Salgaonkar Road Cuffe;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Colorectal cancer; Cytotoxicity; Meloxicam; PEGylated mixed micelles.;

机译：结直肠癌;细胞毒性;甜菜菌;聚乙二醇化的混合胶束。;

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1. Characterization and in vitro Cytotoxicity Evaluation of Meloxicam Loaded PEGylated Mixed Micelles Fabricated Using Quality by Design Approach [J] . Jessy Shaji Ipshita Menon Drug delivery letters . 2015,第3期

机译：通过设计方法使用质量制造美洛昔康载荷的聚乙二醇化混合胶束的表征和体外细胞毒性评价
2. Preparation, optimization, characterization and cytotoxicity in vitro of Baicalin-loaded mixed micelles [J] . Zhang Haiqun, Zhao Lili, Chu Lianjun, Journal of Colloid and Interface Science . 2014,第Null期

机译：黄ical苷混合胶束的体外制备，优化，表征和细胞毒性
3. Olmesartan medoxomil-loaded mixed micelles: Preparation, characterization and in-vitro evaluation [J] . Mohamed A. El-Gendy, Mona I.A. El-Assal, Mina Ibrahim Tadros, Future Journal of Pharmaceutical Sciences . 2017,第2期

机译：载有奥美沙坦酯的混合胶束：制备，表征和体外评估
4. Capecitabine loaded polymeric micelles: Formulation, characterization and cytotoxicity study [C] . Kuchekar A.B., Pawar A.P. 2013 International Conference on Advanced Nanomaterials and Emerging Engineering Technologies . 2013

机译：卡培他滨负载的聚合物胶束：制剂，表征和细胞毒性研究
5. Development and Evaluation of Desoximetasone Loaded Niosomes for Topical Drug Delivery Using Quality by Design (QbD) Approach [D] . Shah, Parinbhai B. 2021

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6. Doxorubicin-loaded cholic acid-polyethyleneimine micelles for targeted delivery of antitumor drugs: synthesis characterization and evaluation of their in vitro cytotoxicity [O] . Muhammad Wahab Amjad, Mohd Cairul Iqbal Mohd Amin, Haliza Katas, 2012

机译：负载阿霉素的胆酸-聚乙烯亚胺胶束用于靶向递送抗肿瘤药物：合成表征和评价其体外细胞毒性
7. Olmesartan medoxomil-loaded mixed micelles: Preparation, characterization and in-vitro evaluation [O] . Mohamed A. El-Gendy, Mona I.A. El-Assal, Mina Ibrahim Tadros, 2017

机译：Olmesartan medoxomil负载的混合胶束：制备，表征和体外评估

Characterization and in vitro Cytotoxicity Evaluation of Meloxicam Loaded PEGylated Mixed Micelles Fabricated Using Quality by Design Approach

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