Association Between Low HIV-1 DNA and Western Blot Reactivity to HIV-1 Pol in Chronically Infected Individuals

Muccini Camilla; Galli Laura; Spagnuolo Vincenzo; Poli Andrea; Rolla Serena; Mastrangelo Andrea; Rinaldi Francesca; Castagna Antonella

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Association Between Low HIV-1 DNA and Western Blot Reactivity to HIV-1 Pol in Chronically Infected Individuals

机译：在慢性感染的个体中，低HIV-1 DNA和Western印迹反应性与HIV-1 Pol之间的关联

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Background: The aim of the study was to evaluate whether negative HIV-1 pol on Western blot (WB) was associated with low HIV-DNA in adults with chronic HIV-1 infection and suppressive antiretroviral therapy.

机译：背景：该研究的目的是评估Western Blot（WB）的阴性HIV-1 POL是否与慢性HIV-1感染和抑制抗逆转录病毒治疗的低HIV-DNA相关。

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来源
《JAIDS: Journal of acquired immune deficiency syndromes》 |2019年第4期|共4页
作者
Muccini Camilla; Galli Laura; Spagnuolo Vincenzo; Poli Andrea; Rolla Serena; Mastrangelo Andrea; Rinaldi Francesca; Castagna Antonella;
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作者单位

Univ Vita Salute San Raffaele Via Stamira DAncona 20 I-20127 Milan Italy;

IRCCS San Raffaele Sci Inst Dept Infect Dis Milan Italy;

Univ Vita Salute San Raffaele Via Stamira DAncona 20 I-20127 Milan Italy;

IRCCS San Raffaele Sci Inst Dept Infect Dis Milan Italy;

IRCCS San Raffaele Sci Inst Dept Microbiol &

Virol Lab Microbiol &

Virol Milan Italy;

Univ Vita Salute San Raffaele Via Stamira DAncona 20 I-20127 Milan Italy;

Univ Florence Dept Expt &

Clin Med Florence Italy;

Univ Vita Salute San Raffaele Via Stamira DAncona 20 I-20127 Milan Italy;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
HIV-1; HIV seronegativity; HIV seropositivity; HIV antibodies; pol proteins; HIV; blotting; Western;

机译：HIV-1;HIV血清效应;HIV血清阳性;HIV抗体;POL蛋白;艾滋病毒;印迹;西方;

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专利

1. Association Between Low HIV-1 DNA and Western Blot Reactivity to HIV-1 Pol in Chronically Infected Individuals [J] . Muccini Camilla, Galli Laura, Spagnuolo Vincenzo, JAIDS: Journal of acquired immune deficiency syndromes . 2019,第4期

机译：在慢性感染的个体中，低HIV-1 DNA和Western印迹反应性与HIV-1 Pol之间的关联
2. Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines. [J] . Paxton WA, Liu R, Kang S, Virology . 1998,第1期

机译：来自未感染的未感染个体的CD4 +淋巴细胞的HIV-1感染力降低：与CCR5的低表达和β-趋化因子的高产生有关。
3. A higher CD4/CD8 ratio correlates with an ultralow cell-associated HIV-1 DNA level in chronically infected patients on antiretroviral therapy: a case control study [J] . Yongsong Yue, Nidan Wang, Yang Han, BMC Infectious Diseases . 2017,第1期

机译：较高的CD4 / CD8比与慢性病毒治疗的慢性感染患者中的超级细胞相关的HIV-1 DNA水平相关：案例对照研究
4. Evaluation of CD8~+ T-Cell-Mediated Selection Pressure on Proviral Gag p17 and p24 in Chronically Infected HIV-1~+ Individuals [C] . Westrop S.J., Mandalia S., Nelson M. and Imami N. European Congress of Immunology . 2009

机译：评估CD8〜+ T细胞介导的选择压力在慢性感染HIV-1〜+个体中的荧光GAG P17和P24
5. IgE anti-HIV-1 in serum of HIV-1 infected children inhibits HIV-1 production in vitro and IgE mediates cytotoxicity against lymphoma cells expressing HIV-1 and peripheral blood mononuclear cells from an HIV-1 seropositive patient [D] . Bluth, Martin Heath. 1997

机译：HIV-1感染儿童血清中的IgE抗HIV-1抑制了HIV-1的体外产生，IgE介导了对HIV-1血清反应阳性患者表达HIV-1的淋巴瘤细胞和外周血单核细胞的细胞毒性
6. Genome-Wide Association Study on the Development of Cross-Reactive Neutralizing Antibodies in HIV-1 Infected Individuals [O] . Zelda Euler, Marit J. van Gils, Brigitte D. Boeser-Nunnink, 2010

机译：在HIV-1感染个体中产生交叉反应中和抗体的全基因组关联研究
7. Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals. [O] . Zelda Euler, Marit J van Gils, Brigitte D Boeser-Nunnink, 2013

机译：关于HIV-1感染个体中交叉反应中和抗体发展的全基因组关联研究。

Association Between Low HIV-1 DNA and Western Blot Reactivity to HIV-1 Pol in Chronically Infected Individuals

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