• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biotechnology Progress >Two-stage culture process for improved production of ganoderic acid by liquid fermentation of higher fungus Ganoderma lucidum
【24h】

Two-stage culture process for improved production of ganoderic acid by liquid fermentation of higher fungus Ganoderma lucidum

机译：分两步培养工艺，通过高级真菌灵芝的液体发酵提高灵芝酸的产量

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Investigations on the impact of pellet size on the cellular oxygen uptake and accumulation of ganoderic acid (GA) suggested the favorable effect of oxygen limitation on GA formation by the higher fungus Ganoderma lucidum. A two-stage fermentation process was thus proposed for enhanced GA production by combining conventional shake-flask fermentation with static culture. A high cell density of 20.9 g of DW/L (DW = dry cell weight) was achieved through a 4-day shake-flask fermentation followed by a 12-day static culture. A change in the cell morphology and a decrease in the sugar consumption rate were observed during the static culture. The GA production in the new two-stage process was considerably enhanced with its content increased from 1.36 (control) to 3.19 mg/100 mg of DW, which was much higher than previously observed.
机译：对颗粒大小对细胞氧吸收和灵芝酸（GA）积累的影响的研究表明，较高的真菌灵芝能有效限制氧对GA形成的影响。因此，提出了一种两步发酵工艺，通过将常规摇瓶发酵与静态培养相结合来提高GA的产量。通过4天的摇瓶发酵，然后进行12天的静态培养，可实现20.9 g DW / L的高细胞密度（DW =干细胞重量）。在静态培养过程中观察到细胞形态的变化和糖消耗率的降低。新的两步法生产的GA显着提高，其含量从1.36（对照）增加到3.19 mg / 100 mg DW，这比以前观察到的要高得多。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号