Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome

Mulkey Sarah B.; Arroyave-Wessel Margarita; Peyton Colleen; Bulas Dorothy I; Fourzali Yamil; Jiang JiJi; Russo Stephanie; McCarter Robert; Msall Michael E.; du Plessis Adre J.; DeBiasi Roberta L.; Cure Carlos

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Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome

机译：没有先天性Zika综合征的子宫Zika病毒暴露的儿童神经发育异常

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Question Do newborns with in utero Zika virus exposure, normal fetal imaging result, and average head circumference measurement at birth have normal neurodevelopmental outcomes? Findings In this cohort study of 70 Colombian infants with in utero Zika virus exposure but without congenital Zika syndrome at birth, multidomain neurodevelopmental assessment scores deviated from normal scores as the children became older. Meaning Findings from this study suggest long-term neurodevelopmental monitoring should be performed for all infants with Zika virus exposure to ascertain the neurodevelopmental implications of the virus that may manifest with older age.

机译：问题在子宫Zika病毒暴露，正常的胎儿成像结果和出生时的平均头周长测量中是否具有正常的神经发育成果？在这队哥伦比亚婴幼儿患有子宫Zika病毒暴露但没有先天性Zika综合征出生时的调查结果，多麦田神经发育评估分数偏离正常得分，因为孩子们变老。这项研究的意思表明，应对Zika病毒暴露的所有婴儿进行长期神经发育监测，以确定病毒可能表现为年龄较大的病毒的神经发育影响。

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《JAMA pediatrics》 |2020年第3期|共8页
作者
Mulkey Sarah B.; Arroyave-Wessel Margarita; Peyton Colleen; Bulas Dorothy I; Fourzali Yamil; Jiang JiJi; Russo Stephanie; McCarter Robert; Msall Michael E.; du Plessis Adre J.; DeBiasi Roberta L.; Cure Carlos;
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作者单位

Childrens Natl Hosp Washington DC 20010 USA;

Childrens Natl Hosp Washington DC 20010 USA;

Northwestern Univ Dept Phys Therapy &

Human Movement Sci Chicago IL 60611 USA;

Childrens Natl Hosp Washington DC 20010 USA;

Sabbag Radiologos Barranquilla Colombia;

Childrens Natl Hosp Washington DC 20010 USA;

Childrens Natl Hosp Washington DC 20010 USA;

Childrens Natl Hosp Washington DC 20010 USA;

Univ Chicago Kennedy Res Ctr Neurodev Disabil Comer Childrens Hosp Chicago IL 60637 USA;

Childrens Natl Hosp Washington DC 20010 USA;

Childrens Natl Hosp Washington DC 20010 USA;

BIOMELAB Barranquilla Colombia;

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正文语种 eng
中图分类儿科学;
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1. Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome [J] . Mulkey Sarah B., Arroyave-Wessel Margarita, Peyton Colleen, JAMA pediatrics . 2020,第3期

机译：没有先天性Zika综合征的子宫Zika病毒暴露的儿童神经发育异常
2. Neurodevelopmental abnormalities in children with in utero Zika virus exposure without congenital Zika syndrome (vol 174, pg 269, 2020) [J] . Mulkey S. B., Arroyave-Wessel M., Peyton C. JAMA pediatrics . 2020,第3期

机译：在没有先天性Zika综合征的Utero Zika病毒暴露中儿童的神经发育异常（Vol 174，PG 269,2020）
3. Serum Proteomics Reveals Alterations in Protease Activity, Axon Guidance, and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome [J] . Macedo-da-Silva Janaina, Rosa-Fernandes Lvia, Barbosa Raquel Hora, Frontiers in Cellular and Infection Microbiology . 2020,第3期

机译：血清蛋白质组学揭示了蛋白酶活性，轴突引导和婴儿的视觉光电传播途径的改变，在没有先天性Zika综合征的Zika病毒中的Uttero暴露于Zika病毒中的婴儿
4. Evaluation of Executive Functions of Children with Down Syndrome and Zika Virus Using Touch Screen Device : Cognitive evaluation of toddlers by touch-screen [C] . Mário de Oliveira Braga Filho, Elvio Marcos Boato, Andrea Amaro Quesada, IEEE International Conference on Cognitive Infocommunications . 2020

机译：触摸屏设备评估唐氏综合症和寨卡病毒患儿的执行功能：触摸屏对幼儿的认知评估
5. A Novel Radiologic Finding to Predict Ophthalmic Abnormalities in Children with Congenital Zika [D] . Vilar Sampaio, Virginia 2019

机译：一种新的放射学发现，以预测先天性Zika儿童眼科异常
6. Serum Proteomics Reveals Alterations in Protease Activity Axon Guidance and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome [O] . Janaina Macedo-da-Silva, Lívia Rosa-Fernandes, Raquel Hora Barbosa, 2020

机译：血清蛋白质组学揭示了蛋白酶活性轴突引导和婴儿的视觉光电传播途径的改变在没有先天性Zika综合征的Zika病毒中的Uttero暴露于Zika病毒中的婴儿
7. Reply to ‘A critical analysis of neurodevelopmental and neurosensory outcomes after 2 years for children with in utero Zika virus exposure’ [O] . Karin Nielsen-Saines, Patricia Brasil, Tara Kerin, 2019

机译：在子宫Zika病毒暴露后2年后回复对2年后神经发育和神经传感结果的关键分析'

Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome

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