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首页> 外文期刊>Alternative therapies in health and medicine >Efficacy of Lianhuaqingwen capsule compared with oseltamivir for influenza A virus infection: a meta-analysis of randomized, controlled trials.
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Efficacy of Lianhuaqingwen capsule compared with oseltamivir for influenza A virus infection: a meta-analysis of randomized, controlled trials.

机译：莲花清温胶囊与奥司他韦相比对甲型流感病毒感染的疗效：一项随机对照试验的荟萃分析。

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In this meta-analysis, the authors review the results of studies on the efficacy of lianhuaqingwen capsule (LHQW-C) compared with oseltamivir in treating influenza A virus infection. The authors searched PubMed, Embase, Wanfang Data, and the China National Knowledge Infrastructure (CNKI) from the date of inception until December 31, 2012. The Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Database of Systematic Reviews (CDSR) were also searched. Five randomized, controlled trials were finally included and analyzed in this review. Compared with individuals treated with oseltamivir, this metaanalysis showed that participants treated with LHQW-C had a shorter duration of (1) fever, weighted mean difference (WMD) = -4.65 (95% CI, -8.91 to -0.38; P = .030); (2) cough, WMD = -9.79 (95% CI, -14.61 to -4.97; P < .0001); (3) sore throat, WMD = -13.01 (95% CI, -21.76 to -4.27; P = .004); and (4) body ache, WMD = -16.68 (95% CI, -32.33 to -1.03; P = .040). The review also found that the efficacy of the 2 treatments on viral shedding was similar with WMD = -0.24 (95% CI, -4.79 to 4.31; P = .920). The authors conclude that LHQW-C was superior to oseltamivir in improving the symptoms of influenza A virus infection.
机译：在这项荟萃分析中，作者回顾了联华清温胶囊（LHQW-C）与奥司他韦治疗甲型流感病毒感染的疗效研究结果。作者自成立之日起至2012年12月31日在PubMed，Embase，Wanfang Data和中国国家知识基础设施（CNKI）中进行了搜索。Cochrane对照试验中心注册系统（CENTRAL）和Cochrane系统评价数据库（CDSR）也进行了搜索。最终纳入了五项随机对照试验，并对本评价进行了分析。与用奥司他韦治疗的个体相比，该荟萃分析显示，接受LHQW-C治疗的参与者发烧时间更短（1），加权平均差（WMD）= -4.65（95％CI，-8.91至-0.38; P =。 030）; （2）咳嗽，WMD = -9.79（95％CI，-14.61至-4.97; P <.0001）; （3）喉咙痛，WMD = -13.01（95％CI，-21.76至-4.27; P = .004）; （4）身体疼痛，WMD = -16.68（95％CI，-32.33至-1.03; P = .040）。该评价还发现，这两种疗法对病毒脱落的功效与WMD = -0.24（95％CI，-4.79至4.31; P = .920）相似。作者得出结论，在改善甲型流感病毒感染症状方面，LHQW-C优于奥司他韦。

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