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首页> 外文期刊>Journal of Animal Physiology and Animal Nutrition >Tonicity of oral rehydration solutions affects water, mineral and acid-base balance in calves with naturally occurring diarrhoea
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Tonicity of oral rehydration solutions affects water, mineral and acid-base balance in calves with naturally occurring diarrhoea

机译:口腔补液溶液的张力会影响牛犊的水,矿物质和酸碱平衡,天然存在腹泻

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Recommendations for composition of oral rehydration solutions (ORS) for calves, particularly concerning Na+, glucose, and their combined effect on tonicity, are not in line with guidelines for humans. Thus, this study aimed to determine the effect of ORS tonicity on water, mineral and acid-base balance. Seventy-two calves were selected based on the severity of dehydration and blood base excess (BE) on day 0. Five calves that did not develop diarrhoea were removed post-inclusion from the study. Calves were allocated to blocks of four animals based on blood BE on day 1. Within each block, calves were randomly assigned to one of four treatments: (a) hypotonic ORS with low Na(+)and lactose (HYPO); (b) isotonic ORS with low Na(+)and glucose (ISO); (c) hypertonic ORS with high Na(+)and glucose (HYPER); and (d) control consisting of warm water including 5 g/L of whey powder (CON). Treatments were administered twice daily over a 3-day period, in which calves were offered 2.0 L of treatment at 1300 and 2100 hr. Calves were fed 2.5 L of milk replacer at 0700 and 1630 hr from day 1 to 3 and 3.0 L from day 4 to 5, and had access to water. Calves were monitored for 5 days in which measurements included intakes, BW, blood sampling and collection of faeces on day 1 and urine from day 1 to 3. All ORS treatments maintained normal serum Na+, whereas CON did not. Calves in the HYPER group had lower blood pH and greater faecal Na(+)losses than HYPO and ISO. Plasma expansion relative to baseline was higher in low tonicity ORS (+4.8%) when compared with CON (+1.0%). Urine osmolality was 30% higher in HYPER calves. In this experiment, low tonicity ORS were more effective at restoring water, mineral and acid-base balance than the hypertonic ORS.
机译:对犊牛的口腔补液溶液(OR)组成的建议,特别是Na +,葡萄糖以及它们对张力的综合影响,并不符合人体指导。因此,本研究旨在确定或张力对水,矿物质和酸碱平衡的影响。根据脱水和血基的严重程度选择七十二个小牛,在第0天的脱水和血基的严重程度。从研究后纳入含有腹泻的五个小牛。将小牛分配给基于血液的四只动物的块。在第1天。在每个嵌段内,小腿随机分配到四种处理中的一种:(a)低钠或乳糖(+)和乳糖(乳糖); (b)等渗或具有低Na(+)和葡萄糖(ISO); (c)高压剂或高Na(+)和葡萄糖(超级); (d)由温水组成的控制,包括5g / L乳清粉(CON)。每天服用两次治疗,在3天的时间内每天进行两次,其中犊牛在1300和2100小时的1300和2100小时提供2.0磅。小牛在0700和1630小时的时间从第1天到3和3.0 L进给2.5升牛奶替代品,从第4天到5日,并获得水。监测小牛5天,其中测量包括摄入量,BW,血液取样和第1天的粪便和尿液收集,尿液从第1天到3日。所有或者治疗保留了正常的血清Na +,而Con没有。高群中的犊牛患有较低的血液pH和更大的粪便Na(+)损失而不是逆血和iso。与CON(+ 1.0%)相比,相对于基线相对于基线相对于基线的血浆膨胀较高。尿液渗透压渗透压渗透压率为30%。在该实验中,低张力或在恢复水,矿物质和酸碱的平衡方面比高渗或酸碱的平衡更有效。

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