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首页> 外文期刊>Journal of biochemical and molecular toxicology >An efficient or methodical review of immunotherapy against breast cancer
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An efficient or methodical review of immunotherapy against breast cancer

机译：对乳腺癌免疫疗法的有效或有条不紊的综述

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Abstract Breast cancer (BC) is one of the most widespread malignancies in women worldwide. Breast cancer is mainly classified into a few key molecular subtypes in accordance with hormone and growth factor receptor expression, etc. In spite of numerous advances in the remedy of breast cancer, the development of metastatic disease remains an untreatable and repeated basis of cancer death for women. Preclinical and clinical studies of immunotherapy in cancer remedy have been in progress for the past quite a few decades by an effort to accelerate, augment, and modulate the immune system to spot and devastate cancer cells. Advancement of cancer immunotherapy is rapidly increasing with eminent and most interesting therapy compared to other therapy like targeted therapy, cytotoxic chemotherapy, radiation as well as surgery. Cancer immunotherapy, also known as biological therapy, which denotes the controlling and by means of the patient's own immune system to goal the cancer cells rather than using an extrinsic therapy. In that way, focusing of cancer immunotherapy developing mediators that stimulates or enhances the immune system's recognition and destroying the cancer cells. This review describes a holistic outlook and deeper understanding of the biology of immunotherapy within the system of tumor microenvironment of breast cancer that improve clinical research and constructive impact on the study conclusion.
机译：摘要乳腺癌（BC）是全球妇女最广泛的恶性肿瘤之一。乳腺癌主要根据激素和生长因子受体表达分为几个关键的分子亚型。尽管乳腺癌的补救措施众多进展，转移性疾病的发展仍然是癌症死亡的无法治疗和重复的基础女性。通过努力加速，增强和调节斑点和破坏性癌细胞的临床和调节免疫系统的临床直接和癌症疗法的临床直接和临床研究已经进入了过去几十年。与靶向治疗，细胞毒性化疗，辐射以及手术等其他治疗相比，癌症免疫疗法的进步迅速增加，最有趣的治疗迅速增加。癌症免疫疗法，也称为生物疗法，其表示控制和通过患者自己的免疫系统来实现癌细胞，而不是使用外本治疗。以这种方式，致力于癌症免疫疗法的培养蛋白刺激或增强免疫系统的识别和破坏癌细胞。本综述描述了整体展望和更深入地了解乳腺癌肿瘤微环境系统内免疫疗法的生物学，改善了对研究结论的临床研究和建设性影响。

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